Sabril and Versed drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Sabril (vigabatrin) and Versed (midazolam hydrochloride). Common drug interactions include seizure among females and respiratory distress among males.
The phase IV clinical study analyzes what interactions people have when they take Sabril and Versed. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.
What is Sabril?
Sabril has active ingredients of vigabatrin. eHealthMe is studying from 12,445 Sabril users. Check the latest studies of Sabril.
What is Versed?
Versed has active ingredients of midazolam hydrochloride. It is often used in sedation during medical procedure. eHealthMe is studying from 6,869 Versed users. Check the latest studies of Versed.
23 people who take Sabril and Versed together, and have interactions are studied.

What are the common drug interactions of Sabril and Versed, by gender? *:
female:
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Diarrhoea
- Decreased appetite
- Aphagia (inability or refusal to swallow)
- Fall
- Grand mal convulsion (a type of generalized seizure that affects the entire brain)
- Hypophagia (reduced food intake)
- Mouth ulceration (mouth ulcers)
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
- Oral pain
male:
- Respiratory distress (difficulty in breathing)
- Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
- Blindness
- Coma (state of unconsciousness lasting more than six hours)
- Decreased activity
- Disturbance in attention
- Hypersensitivity
- Lethargy (tiredness)
- Agitation (state of anxiety or nervous excitement)
- Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs)
What are the common drug interactions of Sabril and Versed, by age (0-1 to 60+)? *:
0-1:
- Respiratory distress (difficulty in breathing)
- Pneumonia
- Cardiogenic shock (inadequate circulation of blood)
- Acute respiratory failure
- Agitation (state of anxiety or nervous excitement)
- Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs)
- Enterovirus infection
- Influenza
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
- Rhinovirus infection
2-9:
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Aphagia (inability or refusal to swallow)
- Fall
- Grand mal convulsion (a type of generalized seizure that affects the entire brain)
- Hypophagia (reduced food intake)
- Mouth ulceration (mouth ulcers)
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
- Oral pain
- Pyrexia (fever)
- Rhinorrhoea (watery mucus discharge from the nose)
10-19:
- Diarrhoea
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Vomiting
- Fatigue (feeling of tiredness)
- Abdominal discomfort
- Constipation
- Decreased appetite
- Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
- Heart rate decreased
- Oxygen saturation decreased
20-29:
- Decreased activity
- Disturbance in attention
- Drug ineffective
- Hypersensitivity
- Lethargy (tiredness)
- Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
30-39:
n/a
40-49:
n/a
50-59:
- Death
60+:
- Aphagia (inability or refusal to swallow)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Lip injury
- Lung disorder (lung disease)
- Metastases to lung (cancer spreads to lung)
- Mouth ulceration (mouth ulcers)
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
- Oral pain
- Pyrexia (fever)
- Rhinorrhoea (watery mucus discharge from the nose)
What are the existing conditions these people have? *
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 8 people, 34.78%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 7 people, 30.43%
- Tuberous Sclerosis (a rare genetic disease that causes benign tumours to grow in the brain and other organs): 5 people, 21.74%
- Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 5 people, 21.74%
- Partial Seizures (seizures which affect only a part of the brain at onset): 3 people, 13.04%
- Complex Partial Seizures (epileptic seizure): 3 people, 13.04%
- Infantile Spasms: 2 people, 8.70%
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 8.70%
- Astrocytoma, Low Grade (low grade tumour of the brain that originate in a particular kind of glial-cells): 2 people, 8.70%
* Approximation only. Some reports may have incomplete information.
Do you take Sabril and Versed?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Sabril and Versed:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Sabril:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Versed:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sabril and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Versed and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on vigabatrin and midazolam hydrochloride (the active ingredients of Sabril and Versed, respectively), and Sabril and Versed (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Urinary Retention and Pneumonia - 5 seconds ago
- Could Vitamin D cause Pancytopenia? - 22 seconds ago
- Could Hydroxyzine cause Hyponatremia? - 23 seconds ago
- Could Hydroxyzine cause Electrolyte Imbalance? - 25 seconds ago
- Rheumatoid Arthritis and Gallbladder Necrosis - 32 seconds ago
- Cardizem vs. Isosorbide Dinitrate, side effect and effectiveness comparison - 49 seconds ago
- Could Xarelto cause Myocardial Strain? - 57 seconds ago
- Drug interactions of Testosterone Cypionate and Profen - a minute ago
- How effective is Tresiba for Type 1 Diabetes? - a minute ago
- Drug interactions of Aranesp and Warfarin Sodium - a minute ago