Saccharomyces and Probiotic drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Saccharomyces (saccharomyces boulardii) and Probiotic (bacillus coagulans). Common drug interactions include thyroid disorder among females and abdominal pain upper among males.

The phase IV clinical study analyzes what interactions people have when they take Saccharomyces and Probiotic. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Saccharomyces?

Saccharomyces has active ingredients of saccharomyces boulardii. eHealthMe is studying from 983 Saccharomyces users. Check the latest studies of Saccharomyces.

What is Probiotic?

Probiotic has active ingredients of bacillus coagulans. It is often used in irritable bowel syndrome. eHealthMe is studying from 22,461 Probiotic users. Check the latest studies of Probiotic.



On Jul, 14, 2026

24 people who take Saccharomyces and Probiotic together, and have interactions are studied.

Saccharomyces and Probiotic drug interactions.

What are the common drug interactions of Saccharomyces and Probiotic, by gender? *:

female:

  1. Thyroid disorder (thyroid diseases)
  2. Tinnitus (a ringing in the ears)
  3. Toothache (tooth pain)
  4. Tremor (trembling or shaking movements in one or more parts of your body)
  5. Urticaria (rash of round, red welts on the skin that itch intensely)
  6. Vertigo
  7. Weight decreased
  8. Fatigue (feeling of tiredness)
  9. Somnolence (a state of near-sleep, a strong desire for sleep)
  10. Vomiting

male:

  1. Abdominal pain upper
  2. Depression
  3. Head discomfort
  4. Impaired healing
  5. Infrequent bowel movements
  6. Insomnia (sleeplessness)
  7. Iron deficiency
  8. Laziness
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Mood altered (changes in mood)

What are the common drug interactions of Saccharomyces and Probiotic, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Dyspnoea (difficult or laboured respiration)
  2. Fear
  3. Haematochezia (passage of stools containing blood)
  4. Haemorrhoids (a swollen vein or group of veins in the region of the anus)
  5. Headache (pain in head)
  6. Palpitations (feelings or sensations that your heart is pounding or racing)
  7. Suicidal ideation
  8. Tachycardia paroxysmal (a form of tachycardia which begins and ends in an acute (or paroxysmal) manner)
  9. Weight decreased
  10. Brain injury

30-39:

  1. Anxiety
  2. Depression
  3. Fatigue (feeling of tiredness)
  4. Tinnitus (a ringing in the ears)
  5. Abdominal discomfort
  6. Abdominal pain upper
  7. Asthenia (weakness)
  8. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  9. Depressed mood
  10. Dizziness

40-49:

  1. Abdominal pain upper
  2. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  3. Dyspnoea (difficult or laboured respiration)
  4. Hyperhidrosis (abnormally increased sweating)
  5. Nausea (feeling of having an urge to vomit)
  6. Palpitations (feelings or sensations that your heart is pounding or racing)
  7. Pyrexia (fever)
  8. Vomiting

50-59:

  1. Ingrowing nail
  2. Intervertebral disc degeneration (spinal disc degeneration)
  3. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  4. Pneumonia
  5. Tendon rupture (tear of tendon)
  6. Vomiting
  7. Abdominal pain
  8. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  9. Diarrhoea
  10. Exostosis (formation of new bone on the surface of a bone)

60+:

  1. Fatigue (feeling of tiredness)
  2. Somnolence (a state of near-sleep, a strong desire for sleep)
  3. Spinal column stenosis (narrowing of spinal column)
  4. Dyslexia (disorders that involve difficulty in learning to read or interpret words, letters, and other symbols)
  5. Spinal stenosis (narrowing of spinal column)

What are the existing conditions these people have? *

  1. Lyme Disease (a bacterial infection that is spread to humans by infected ticks): 7 people, 29.17%
  2. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 12.50%
  3. Neuropathy Peripheral (surface nerve damage): 3 people, 12.50%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 8.33%
  5. Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 2 people, 8.33%
  6. Pain: 2 people, 8.33%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Saccharomyces and Probiotic?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Saccharomyces and Probiotic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Saccharomyces:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Probiotic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Saccharomyces and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Probiotic and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on saccharomyces boulardii and bacillus coagulans (the active ingredients of Saccharomyces and Probiotic, respectively), and Saccharomyces and Probiotic (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: