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Salagen and Rocephin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Salagen (pilocarpine hydrochloride) and Rocephin (ceftriaxone sodium). Common drug interactions include pain among females.

The phase IV clinical study analyzes what interactions people have when they take Salagen and Rocephin. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Salagen?

Salagen has active ingredients of pilocarpine hydrochloride. It is often used in sjogren syndrome. eHealthMe is studying from 1,966 Salagen users. Check the latest studies of Salagen.

What is Rocephin?

Rocephin has active ingredients of ceftriaxone sodium. It is often used in infection. eHealthMe is studying from 15,665 Rocephin users. Check the latest studies of Rocephin.

On Jul, 15, 2026

32 people who take Salagen and Rocephin together, and have interactions are studied.

Salagen and Rocephin drug interactions.

What are the common drug interactions of Salagen and Rocephin, by gender? *:

female:

  1. Pain
  2. Appendicitis (inflammation of the appendix)
  3. Dental caries
  4. Diarrhoea
  5. Enteritis (inflammation of the small intestine)
  6. Enterococcal infection
  7. Escherichia infection (bacterial infection by escherichia coli)
  8. Essential thrombocythaemia (chronic blood cancer)
  9. Exostosis (formation of new bone on the surface of a bone)
  10. Facial neuralgia (pain of face)

male:

n/a

What are the common drug interactions of Salagen and Rocephin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Appendicitis (inflammation of the appendix)
  2. Aptyalism (deficiency or absence of saliva)
  3. Diarrhoea
  4. Enteritis (inflammation of the small intestine)
  5. Enterococcal infection
  6. Escherichia infection (bacterial infection by escherichia coli)
  7. Essential thrombocythaemia (chronic blood cancer)
  8. Exostosis (formation of new bone on the surface of a bone)
  9. Facial neuralgia (pain of face)
  10. Foot fracture

60+:

n/a

What are the existing conditions these people have? *

  1. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 30 people, 93.75%
  2. Osteoporosis (bones weak and more likely to break): 28 people, 87.50%
  3. Thrombocytopenia (decrease of platelets in blood): 11 people, 34.38%

* Approximation only. Some reports may have incomplete information.

Do you take Salagen and Rocephin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Salagen and Rocephin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Salagen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Rocephin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Salagen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Rocephin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on pilocarpine hydrochloride and ceftriaxone sodium (the active ingredients of Salagen and Rocephin, respectively), and Salagen and Rocephin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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