Santyl and Ativan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Santyl (collagenase) and Ativan (lorazepam). Common drug interactions include joint range of motion decreased among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Santyl and Ativan. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Santyl?

Santyl has active ingredients of collagenase. eHealthMe is studying from 1,479 Santyl users. Check the latest studies of Santyl.

What is Ativan?

Ativan has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 78,506 Ativan users. Check the latest studies of Ativan.

On Aug, 05, 2026

24 people who take Santyl and Ativan together, and have interactions are studied.

What are the common drug interactions of Santyl and Ativan, by gender? *:

female:

Joint range of motion decreased (disease of joint movement)
Arthralgia (joint pain)
Injury
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Oedema peripheral (superficial swelling)
Pain
Activities of daily living impaired
B precursor type acute leukaemia (lymphoid cancer)
Graft versus host disease in skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin)
Mucosal dryness (dryness of mucous membrane)

male:

Anaemia (lack of blood)
Asthenia (weakness)
Colostomy
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Impaired healing
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Renal cell carcinoma (a kidney cancer)
Respiratory tract infection
Application site discolouration
Cellulitis (infection under the skin)

What are the common drug interactions of Santyl and Ativan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cellulitis (infection under the skin)
Dysphagia (a condition in which swallowing is difficult or painful)
Hypertension (high blood pressure)
Hypotension (abnormally low blood pressure)
Nausea (feeling of having an urge to vomit)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pharyngolaryngeal pain
Staphylococcal bacteraemia (a bacterial infection of blood)
Tonsillar disorder (disease of tonsil)
Wound infection

40-49:

n/a

50-59:

Injury
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Pain
Asthenia (weakness)
Activities of daily living impaired
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Emotional distress
Joint range of motion decreased (disease of joint movement)
Mobility decreased (ability to move is reduced)
Pruritus (severe itching of the skin)

60+:

Anaemia (lack of blood)
Febrile neutropenia (fever with reduced white blood cells)
Death
Dysphonia (speech disorder attributable to a disorder of phonation)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Respiratory failure (inadequate gas exchange by the respiratory system)
Wound secretion
Malignant neoplasm progression (cancer tumour came back)
Platelet count decreased
Pneumonia

What are the existing conditions these people have? *

Pain: 6 people, 25.00%
Nausea (feeling of having an urge to vomit): 4 people, 16.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 16.67%
Constipation: 4 people, 16.67%
Sleep Disorder: 3 people, 12.50%
Neuralgia (pain in one or more nerves): 3 people, 12.50%
Insomnia (sleeplessness): 3 people, 12.50%
Indigestion: 3 people, 12.50%
Hyperkalemia (damage to or disease of the kidney): 3 people, 12.50%
B-Cell Type Acute Leukaemia (cancer of the white blood cells): 3 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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