Se and Valproate sodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Se (selenium) and Valproate sodium (valproate sodium). Common drug interactions include adverse event among females and psychomotor skills impaired among males.

The phase IV clinical study analyzes what interactions people have when they take Se and Valproate sodium. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Se?

Se has active ingredients of selenium. eHealthMe is studying from 5,604 Se users. Check the latest studies of Se.

What is Valproate sodium?

Valproate sodium has active ingredients of valproate sodium. It is often used in epilepsy. eHealthMe is studying from 24,044 Valproate sodium users. Check the latest studies of Valproate sodium.



On Jul, 09, 2026

11 people who take Se and Valproate sodium together, and have interactions are studied.

Se and Valproate sodium drug interactions.

What are the common drug interactions of Se and Valproate Sodium, by gender? *:

female:

  1. Adverse event
  2. Asphyxia (a condition in which there is an extreme decrease in the concentration of oxygen in the body)
  3. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  4. Productive cough
  5. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
  6. Abdominal discomfort
  7. Ageusia (loss of taste functions of the tongue)
  8. Alopecia (absence of hair from areas of the body)
  9. Arthralgia (joint pain)
  10. Breast cancer stage iv

male:

  1. Psychomotor skills impaired
  2. Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
  3. Foetal heart rate disorder
  4. Foetal malnutrition (soft tissue wasting at birth)
  5. Jaundice neonatal (yellowing of skin in neonate)
  6. Learning disorder (the brain's disability to receive, process, store, respond to and communicate information)
  7. Limb malformation (abnormal birth defect of leg)
  8. Obesity (having too much body fat)
  9. Psychomotor retardation (motor mental retardation)
  10. Pyelonephritis (inflammation of kidney caused by bacteria)

What are the common drug interactions of Se and Valproate Sodium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Decreased appetite
  2. Dry skin
  3. Dystonia (abnormal muscle tone)
  4. Erythema (redness of the skin)
  5. Fatigue (feeling of tiredness)
  6. Insomnia (sleeplessness)
  7. Neoplasm skin (skin tumour)
  8. Pain of skin
  9. Rash
  10. Skin exfoliation (removal of the oldest dead skin cells)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Adverse event
  2. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)

What are the existing conditions these people have? *

  1. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 5 people, 45.45%
  2. Torticollis (a twisted neck in which the head is tipped to one side, while the chin is turned to the other): 1 person, 9.09%
  3. Sleep Disorder: 1 person, 9.09%
  4. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 9.09%
  5. Schizoaffective Disorder (a mental disorder characterized by disordered thought): 1 person, 9.09%
  6. Oral Pain: 1 person, 9.09%
  7. Muscle Spasms (muscle contraction): 1 person, 9.09%
  8. Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 1 person, 9.09%
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 9.09%
  10. High Blood Pressure: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Se and Valproate sodium?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Se and Valproate sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Se:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Valproate sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Se and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Valproate sodium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on selenium and valproate sodium (the active ingredients of Se and Valproate sodium, respectively), and Se and Valproate sodium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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