Selenium and Xifaxan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Selenium (selenium) and Xifaxan (rifaximin). Common drug interactions include fatigue among females and cardiac arrest among males.

The phase IV clinical study analyzes what interactions people have when they take Selenium and Xifaxan. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Selenium?

Selenium has active ingredients of selenium. It is often used in vitamin supplementation. eHealthMe is studying from 5,314 Selenium users. Check the latest studies of Selenium.

What is Xifaxan?

Xifaxan has active ingredients of rifaximin. It is often used in irritable bowel syndrome. eHealthMe is studying from 16,609 Xifaxan users. Check the latest studies of Xifaxan.

On Jul, 13, 2026

22 people who take Selenium and Xifaxan together, and have interactions are studied.

What are the common drug interactions of Selenium and Xifaxan, by gender? *:

female:

Fatigue (feeling of tiredness)
Constipation
Epistaxis (bleed from the nose)
Food craving
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Herpes virus infection
Infusion site scar
Infusion site swelling
Oral pain
Skin ulcer

male:

Cardiac arrest
Eating disorder
Haematemesis (vomiting of blood)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Melaena (the passage of black, tarry stools)
Oesophageal varices haemorrhage (bleeding from extremely dilated sub-mucosal veins in the lower third of the oesophagus)
Oropharyngeal pain
Hospitalisation

What are the common drug interactions of Selenium and Xifaxan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Diarrhoea
Insomnia (sleeplessness)
Therapeutic response unexpected

30-39:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arthralgia (joint pain)
Body temperature decreased
Body temperature increased
Dizziness
Emotional distress
Headache (pain in head)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Malaise (a feeling of general discomfort or uneasiness)

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arthralgia (joint pain)
Body temperature decreased
Body temperature increased
Dizziness
Emotional distress
Headache (pain in head)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Malaise (a feeling of general discomfort or uneasiness)

50-59:

Hypersomnia (excessive daytime sleepiness (eds))
Immune system disorder
Pathogen resistance
Upper respiratory tract infection
Urinary tract infection

60+:

Cardiac arrest
Eating disorder
Blood bilirubin increased
Fall
Fatigue (feeling of tiredness)
Headache (pain in head)
Heart rate increased
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hospitalisation
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 6 people, 27.27%
Pain: 3 people, 13.64%
Hereditary Angioedema (recurrent episodes of severe swelling): 3 people, 13.64%
Pulmonary Embolism (blockage of the main artery of the lung): 2 people, 9.09%
Primary Intestinal Pseudo-Obstruction (symptoms of intestinal blockage without any physical signs of a blockage): 2 people, 9.09%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 2 people, 9.09%
Nausea And Vomiting: 2 people, 9.09%
Nausea (feeling of having an urge to vomit): 2 people, 9.09%
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking): 2 people, 9.09%
Iron Deficiency Anaemia: 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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