Senna and Atropine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Senna (senna) and Atropine (atropine). Common drug interactions include fall among females and seizure among males.

The phase IV clinical study analyzes what interactions people have when they take Senna and Atropine. It is created by eHealthMe based on reports of 92 people who take the same drugs from the FDA, and is updated regularly.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.

What is Atropine?

Atropine has active ingredients of atropine. eHealthMe is studying from 8,693 Atropine users. Check the latest studies of Atropine.



On Jul, 05, 2026

92 people who take Senna and Atropine together, and have interactions are studied.

Senna and Atropine drug interactions.

What are the common drug interactions of Senna and Atropine, by gender? *:

female:

  1. Fall
  2. Dyspnoea (difficult or laboured respiration)
  3. Dizziness
  4. Nausea (feeling of having an urge to vomit)
  5. Weight decreased
  6. Dehydration (dryness resulting from the removal of water)
  7. Abdominal pain
  8. Balance disorder
  9. Cardiac failure congestive
  10. Multiple injuries

male:

  1. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  2. Acute respiratory failure
  3. Back pain
  4. Cardiac arrest
  5. Diarrhoea
  6. Fall
  7. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  8. Asthenia (weakness)
  9. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  10. Fatigue (feeling of tiredness)

What are the common drug interactions of Senna and Atropine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  2. Acute respiratory failure
  3. Pyrexia (fever)
  4. Respiratory tract infection
  5. Biliary tract disorder
  6. Cardiac arrest
  7. Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
  8. Enterobacter infection (infection caused by bacteria of the family enterobacteriaceae)
  9. Gastritis (inflammation of stomach)
  10. Hypotension (abnormally low blood pressure)

10-19:

n/a

20-29:

  1. Haematocrit decreased
  2. Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)
  3. Adenoma benign (non-cancerous tumour -secreting)
  4. Adnexa uteri cyst (ovarian cysts)
  5. Allergic sinusitis
  6. Anxiety
  7. Aortic arteriosclerosis (hardening of the aortic arteries)
  8. Aortic calcification (aortic calcification sign of heart valve disease)
  9. Aortic valve sclerosis (narrowing of the aortic valve)
  10. Arthralgia (joint pain)

30-39:

  1. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  2. Pulmonary embolism (blockage of the main artery of the lung)
  3. Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)

40-49:

  1. Diarrhoea
  2. Vomiting
  3. Dehydration (dryness resulting from the removal of water)
  4. Palpitations (feelings or sensations that your heart is pounding or racing)
  5. Hypovolaemia (a decreased volume of circulating blood in the body)
  6. Abdominal pain lower
  7. Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
  8. Ataxia (loss of full control of bodily movements)
  9. Atrophy (wasting away of a part of the body)
  10. Back injury

50-59:

  1. Abdominal discomfort
  2. Ageusia (loss of taste functions of the tongue)
  3. Agitation (state of anxiety or nervous excitement)
  4. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  5. Anaemia (lack of blood)
  6. Anosmia (partial or complete loss of the sense of smell)
  7. Anxiety
  8. Arthralgia (joint pain)
  9. Ascites (accumulation of fluid in the abdominal cavity)
  10. Asthenia (weakness)

60+:

  1. Fall
  2. Asthenia (weakness)
  3. Balance disorder
  4. Cardiac arrest
  5. Confusional state
  6. Fatigue (feeling of tiredness)
  7. Multiple injuries
  8. Pain
  9. Pneumonia
  10. Dehydration (dryness resulting from the removal of water)

What are the existing conditions these people have? *

  1. Pain: 16 people, 17.39%
  2. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 10 people, 10.87%
  3. Stress And Anxiety: 8 people, 8.70%
  4. Nausea (feeling of having an urge to vomit): 8 people, 8.70%
  5. Pancreatic Carcinoma (pancreatic cancer): 7 people, 7.61%
  6. Multiple Myeloma (cancer of the plasma cells): 7 people, 7.61%
  7. Diarrhea: 6 people, 6.52%
  8. Nausea And Vomiting: 5 people, 5.43%
  9. High Blood Pressure: 5 people, 5.43%

* Approximation only. Some reports may have incomplete information.

Do you take Senna and Atropine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Senna and Atropine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Senna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Atropine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Senna and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Atropine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on senna and atropine (the active ingredients of Senna and Atropine, respectively), and Senna and Atropine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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