Senna and Embolex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Senna (senna) and Embolex (dihydroergotamine mesylate; heparin sodium; lidocaine hydrochloride). Common drug interactions include brain injury among females.

The phase IV clinical study analyzes what interactions people have when they take Senna and Embolex. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.

What is Embolex?

Embolex has active ingredients of dihydroergotamine mesylate; heparin sodium; lidocaine hydrochloride. eHealthMe is studying from 1,161 Embolex users. Check the latest studies of Embolex.

On Aug, 08, 2026

15 people who take Senna and Embolex together, and have interactions are studied.

What are the common drug interactions of Senna and Embolex, by gender? *:

female:

Brain injury
Renal failure (kidney dysfunction)
Pruritus (severe itching of the skin)
Rash
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood creatinine increased
Blood lactate dehydrogenase increased
Blood urea increased

male:

n/a

What are the common drug interactions of Senna and Embolex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Brain injury
Renal failure (kidney dysfunction)
Pruritus (severe itching of the skin)
Rash
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood creatinine increased
Blood lactate dehydrogenase increased
Blood urea increased

60+:

n/a

What are the existing conditions these people have? *

Systemic Sclerosis (Scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 15 people, 100.00%
High Blood Pressure: 15 people, 100.00%
Acute Kidney Failure: 15 people, 100.00%
Anaemia (lack of blood): 15 people, 100.00%
Arrhythmias (irregular heartbeat): 15 people, 100.00%
Fever: 15 people, 100.00%
Sleep Disorder: 15 people, 100.00%
Heart Disease: 15 people, 100.00%
Infection: 15 people, 100.00%
Hypersensitivity: 13 people, 86.67%

* Approximation only. Some reports may have incomplete information.

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