Senna and Grape drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Senna (senna) and Grape (grape). Common drug interactions include pruritus among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Senna and Grape. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.

What is Grape?

Grape has active ingredients of grape. eHealthMe is studying from 1,229 Grape users. Check the latest studies of Grape.



On Jul, 08, 2026

23 people who take Senna and Grape together, and have interactions are studied.

Senna and Grape drug interactions.

What are the common drug interactions of Senna and Grape, by gender? *:

female:

  1. Pruritus (severe itching of the skin)
  2. Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
  3. Stomatitis (inflammation of mucous membrane of mouth)
  4. Tooth extraction
  5. Varicose vein (veins that have become enlarged and tortuous)
  6. Abdominal pain
  7. Adrenal disorder
  8. Adrenal mass
  9. Back pain
  10. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)

male:

  1. Fatigue (feeling of tiredness)
  2. Abdominal pain
  3. Dyspnoea (difficult or laboured respiration)
  4. Faeces hard
  5. Febrile neutropenia (fever with reduced white blood cells)
  6. Haematuria (presence of blood in urine)
  7. Haemorrhoids (a swollen vein or group of veins in the region of the anus)
  8. Hypotension (abnormally low blood pressure)
  9. Loose tooth
  10. Malignant neoplasm progression (cancer tumour came back)

What are the common drug interactions of Senna and Grape, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Allergy to metals
  2. Perfume sensitivity

40-49:

  1. Blood pressure increased
  2. Bone disorder
  3. Cardiac disorder
  4. Cellulitis (infection under the skin)
  5. Decreased interest
  6. Depression
  7. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  8. Diarrhoea
  9. Dizziness
  10. Excoriation (to tear or wear off the skin of)

50-59:

n/a

60+:

  1. Cellulitis (infection under the skin)
  2. Abdominal pain
  3. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  4. Anxiety
  5. Aortic arteriosclerosis (hardening of the aortic arteries)
  6. Aphthous stomatitis (mouth ulcer)
  7. Arthralgia (joint pain)
  8. Blood glucose increased
  9. Blood pressure increased
  10. Blood testosterone increased

What are the existing conditions these people have? *

  1. Quit Smoking: 11 people, 47.83%
  2. Breast Cancer: 11 people, 47.83%
  3. Bone Neoplasm Malignant (cancer of bone): 10 people, 43.48%
  4. Bone Loss: 7 people, 30.43%
  5. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 21.74%
  6. Bone Density Decreased: 4 people, 17.39%
  7. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 8.70%
  8. Multiple Myeloma (cancer of the plasma cells): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Senna and Grape?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Senna and Grape:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Senna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Grape:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Senna and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Grape and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on senna and grape (the active ingredients of Senna and Grape, respectively), and Senna and Grape (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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