Senna and Nplate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Senna (senna) and Nplate (romiplostim). Common drug interactions include pancreatic carcinoma stage ii among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Senna and Nplate. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.

What is Nplate?

Nplate has active ingredients of romiplostim. It is often used in idiopathic thrombocytopenic purpura (itp). eHealthMe is studying from 17,850 Nplate users. Check the latest studies of Nplate.

On Aug, 01, 2026

40 people who take Senna and Nplate together, and have interactions are studied.

What are the common drug interactions of Senna and Nplate, by gender? *:

female:

Pancreatic carcinoma stage ii (pancreatic cancer stage ii)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Petechiae (a small red or purple spot caused by bleeding into the skin)
Pyrexia (fever)
Renal failure (kidney dysfunction)
Respiratory distress (difficulty in breathing)
Subdural haematoma (blood collects between the skull and the surface of the brain)
Thrombocytopenia (decrease of platelets in blood)
Urinary tract infection
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

male:

Cardiac failure congestive
Cardiac death
Chest pain
Cough
Diarrhoea
Epistaxis (bleed from the nose)
Eye infection fungal
Failure to thrive (inadequate weight gain and physical growth in children)
Fall
Haemorrhagic anaemia (anaemia due to excessive bleeding)

What are the common drug interactions of Senna and Nplate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
Abdominal hernia
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Lung neoplasm (tumour of lung)
Pleural effusion (water on the lungs)
Pulmonary embolism (blockage of the main artery of the lung)

50-59:

Weight decreased
Bowel movement irregularity
Breast cancer metastatic
Cachexia (loss of weight)
Epistaxis (bleed from the nose)
Erosive oesophagitis (acid reflux disease can cause tissue damage in the oesophagus over time)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Neoplasm malignant (cancer tumour)
Transaminases increased

60+:

Cardiac failure congestive
Fall
Nausea (feeling of having an urge to vomit)
Subdural haematoma (blood collects between the skull and the surface of the brain)
Abdominal pain
Aphasia (damage to the parts of the brain that control language)
Asthenia (weakness)
Cachexia (loss of weight)
Chest pain
Colon cancer

What are the existing conditions these people have? *

Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 32 people, 80.00%
Pain: 3 people, 7.50%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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