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Senna and Protelos drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Senna (senna) and Protelos (strontium ranelate). Common drug interactions include blood creatine phosphokinase increased among females.

The phase IV clinical study analyzes what interactions people have when they take Senna and Protelos. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.

What is Protelos?

Protelos has active ingredients of strontium ranelate. It is often used in osteoporosis. eHealthMe is studying from 302 Protelos users. Check the latest studies of Protelos.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

12 people who take Senna and Protelos together, and have interactions are studied.

Senna and Protelos drug interactions.

What are the common drug interactions of Senna and Protelos, by gender? *:

female:

  1. Blood creatine phosphokinase increased
  2. Grand mal convulsion (a type of generalized seizure that affects the entire brain)
  3. Confusional state
  4. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  5. Urinary tract infection
  6. Fall
  7. Syncope (loss of consciousness with an inability to maintain postural tone)

male:

n/a

What are the common drug interactions of Senna and Protelos, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Blood creatine phosphokinase increased
  2. Grand mal convulsion (a type of generalized seizure that affects the entire brain)
  3. Confusional state
  4. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  5. Urinary tract infection
  6. Fall
  7. Syncope (loss of consciousness with an inability to maintain postural tone)

What are the existing conditions these people have? *

  1. Urinary Tract Infection: 8 people, 66.67%
  2. Grand Mal Convulsion (a type of generalized seizure that affects the entire brain): 5 people, 41.67%
  3. Dementia (madness): 5 people, 41.67%

* Approximation only. Some reports may have incomplete information.

Do you take Senna and Protelos?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Senna and Protelos:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Senna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Protelos:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Senna and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Protelos and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on senna and strontium ranelate (the active ingredients of Senna and Protelos, respectively), and Senna and Protelos (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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