Senna and Xopenex hfa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Senna (senna) and Xopenex hfa (levalbuterol tartrate). Common drug interactions include acute sinusitis among females and abdominal pain upper among males.

The phase IV clinical study analyzes what interactions people have when they take Senna and Xopenex hfa. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.

What is Xopenex hfa?

Xopenex hfa has active ingredients of levalbuterol tartrate. It is often used in asthma. eHealthMe is studying from 2,529 Xopenex hfa users. Check the latest studies of Xopenex hfa.



On Aug, 03, 2026

41 people who take Senna and Xopenex hfa together, and have interactions are studied.

Senna and Xopenex hfa drug interactions.

What are the common drug interactions of Senna and Xopenex Hfa, by gender? *:

female:

  1. Acute sinusitis
  2. Gallbladder enlargement
  3. Gastroenteritis (inflammation of stomach and intestine)
  4. Injection site pain
  5. Chronic gastritis (long lasting infection of stomach lining)
  6. Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
  7. Appendicitis (inflammation of the appendix)
  8. Arthralgia (joint pain)
  9. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  10. Fall

male:

  1. Abdominal pain upper
  2. Hypoprothrombinaemia (blood disorder in which a deficiency of prothrombin (factor ii) results in impaired blood clotting)
  3. Aspartate aminotransferase increased
  4. Bilirubin conjugated increased
  5. Blood bilirubin unconjugated increased
  6. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  7. Disease progression
  8. Eye pain
  9. Pulmonary function test decreased
  10. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)

What are the common drug interactions of Senna and Xopenex Hfa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Hypoprothrombinaemia (blood disorder in which a deficiency of prothrombin (factor ii) results in impaired blood clotting)
  2. International normalised ratio increased
  3. Oxygen saturation decreased
  4. Pancreatitis (inflammation of pancreas)
  5. Restlessness (not able to rest)
  6. Activated partial thromboplastin time prolonged
  7. Alanine aminotransferase increased
  8. Aspartate aminotransferase increased
  9. Bilirubin conjugated increased
  10. Blood bilirubin unconjugated increased

20-29:

n/a

30-39:

  1. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)

40-49:

  1. Blood pressure decreased
  2. Blood urine present
  3. Chronic kidney disease
  4. Dizziness
  5. Neuropathy peripheral (surface nerve damage)
  6. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  7. Pulmonary embolism (blockage of the main artery of the lung)

50-59:

n/a

60+:

  1. Acute sinusitis
  2. Gallbladder enlargement
  3. Iron deficiency anaemia
  4. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
  5. Pain in extremity
  6. Torticollis (a twisted neck in which the head is tipped to one side, while the chin is turned to the other)
  7. Dermal cyst
  8. Fall
  9. Sinusitis (inflammation of sinus)
  10. Urticaria (rash of round, red welts on the skin that itch intensely)

What are the existing conditions these people have? *

  1. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 12 people, 29.27%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 29.27%
  3. Type 2 Diabetes: 11 people, 26.83%
  4. Dizziness: 11 people, 26.83%
  5. Fibromyalgia (a long-term condition which causes pain all over the body): 11 people, 26.83%
  6. High Blood Pressure: 11 people, 26.83%
  7. Sinusitis (inflammation of sinus): 11 people, 26.83%
  8. Seasonal Allergy (allergic condition due to certain season): 11 people, 26.83%
  9. Paranasal Sinus Discomfort: 10 people, 24.39%
  10. Hyperlipidaemia (presence of excess lipids in the blood): 10 people, 24.39%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Senna and Xopenex hfa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Senna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Xopenex hfa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Senna and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xopenex hfa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on senna and levalbuterol tartrate (the active ingredients of Senna and Xopenex hfa, respectively), and Senna and Xopenex hfa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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