Septra and Proair hfa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Septra (sulfamethoxazole; trimethoprim) and Proair hfa (albuterol sulfate). Common drug interactions include euphoric mood among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Septra and Proair hfa. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Septra?

Septra has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 10,280 Septra users. Check the latest studies of Septra.

What is Proair hfa?

Proair hfa has active ingredients of albuterol sulfate. It is often used in asthma. eHealthMe is studying from 53,227 Proair hfa users. Check the latest studies of Proair hfa.

On Aug, 05, 2026

45 people who take Septra and Proair hfa together, and have interactions are studied.

Septra and Proair hfa drug interactions.

What are the common drug interactions of Septra and Proair Hfa, by gender? *:

female:

Euphoric mood (excessively happy but may become angry or irritable)
Face oedema (swelling of face)
Fall
Fatigue (feeling of tiredness)
Fear
Gastric haemorrhage (bleeding stomach)
Gastrointestinal motility disorder (abnormal intestinal contractions)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haematemesis (vomiting of blood)
Hallucination (an experience involving the perception of something not present)

male:

Pneumonia
Anxiety
Cardiac arrest
Emotional distress
Pain
Accident
Arthralgia (joint pain)
Back injury
Back pain
Blood creatinine increased

What are the common drug interactions of Septra and Proair Hfa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Pneumonia

20-29:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Depression
Emotional distress
General physical health deterioration (weak health status)
Injury
Pain
Uterine perforation (accidental puncture of the uterus)

30-39:

Anaemia (lack of blood)
Blood iron decreased
Connective tissue disorder (any disease that has the connective tissues of the body)
Gastric haemorrhage (bleeding stomach)
Haematemesis (vomiting of blood)
Hypotension (abnormally low blood pressure)

40-49:

Chronic kidney disease
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Emotional distress
Limb discomfort (discomfort in leg)
Oedema peripheral (superficial swelling)
Pain
Pain in extremity
Hypersensitivity
Drug ineffective
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Dyspepsia (indigestion)
Emotional distress
Multiple fractures
Osteoporosis (bones weak and more likely to break)
Pain
Renal injury (kidney injury)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

60+:

Contusion (a type of hematoma of tissue in which capillaries)
Accident
Enterococcal infection
Neutropenia (an abnormally low number of neutrophils)
Renal failure acute (rapid kidney dysfunction)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac arrest
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Drug ineffective
Fall

What are the existing conditions these people have? *

Pain: 10 people, 22.22%
High Blood Cholesterol: 9 people, 20.00%
Depression: 8 people, 17.78%
Multiple Myeloma (cancer of the plasma cells): 7 people, 15.56%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 15.56%
Dyspnea (difficult or laboured breathing): 6 people, 13.33%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 13.33%
Blood Glucose Abnormal: 5 people, 11.11%
Blood Pressure Abnormal: 5 people, 11.11%
Infection: 5 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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