Septra and Se drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Septra (sulfamethoxazole; trimethoprim) and Se (selenium). Common drug interactions include drug hypersensitivity among females and blood creatinine increased among males.

The phase IV clinical study analyzes what interactions people have when they take Septra and Se. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Septra?

Septra has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 10,280 Septra users. Check the latest studies of Septra.

What is Se?

Se has active ingredients of selenium. eHealthMe is studying from 5,604 Se users. Check the latest studies of Se.

On Jul, 12, 2026

13 people who take Septra and Se together, and have interactions are studied.

What are the common drug interactions of Septra and Se, by gender? *:

female:

Drug hypersensitivity

male:

Blood creatinine increased
Haemoglobin decreased
Blood urine present
C-reactive protein increased
Campylobacter infection (infection by the campylobacter bacterium)
Cough
Dyspnoea (difficult or laboured respiration)
Eye haemorrhage (bleeding in the eye)
Herpes simplex (herpes simplex is a common viral infection)
Ill-defined disorder

What are the common drug interactions of Septra and Se, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal discomfort
Alanine aminotransferase increased
Ascites (accumulation of fluid in the abdominal cavity)
Gamma-glutamyltransferase increased
Hepatic failure (liver failure)
Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Vomiting

50-59:

Aspergillus test positive
Blood creatinine increased
Blood urine present
C-reactive protein increased
Campylobacter infection (infection by the campylobacter bacterium)
Cough
Dyspnoea (difficult or laboured respiration)
Erythema (redness of the skin)
Eye haemorrhage (bleeding in the eye)
Haemoglobin decreased

60+:

Actinic keratosis (skin disease due to sun exposure)
Anaemia (lack of blood)
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Basal ganglion degeneration (loss of brain tissue in the cortex, or outer layer of the brain)
Blood calcium decreased
Blood chloride increased
Blood creatinine increased
Blood pressure decreased
Blood pressure systolic increased
Blood urea increased

What are the existing conditions these people have? *

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 4 people, 30.77%
Bone Loss: 4 people, 30.77%
Vasculitis (inflammation of a blood vessel or blood vessels): 3 people, 23.08%
Paronychia (infection in the tissues adjacent to a nail on a finger or toe): 2 people, 15.38%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 15.38%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 15.38%
Skin Disorder (skin disease): 1 person, 7.69%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 7.69%
Metastases To Bone (cancer spreads to bone): 1 person, 7.69%
Hypokalemia (low potassium): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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