Septra and Temsirolimus drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Septra (sulfamethoxazole; trimethoprim) and Temsirolimus (temsirolimus). Common drug interactions include encephalopathy among females and groin pain among males.
The phase IV clinical study analyzes what interactions people have when they take Septra and Temsirolimus. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Septra?
Septra has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 10,280 Septra users. Check the latest studies of Septra.
What is Temsirolimus?
Temsirolimus has active ingredients of temsirolimus. eHealthMe is studying from 3,573 Temsirolimus users. Check the latest studies of Temsirolimus.
12 people who take Septra and Temsirolimus together, and have interactions are studied.

What are the common drug interactions of Septra and Temsirolimus, by gender? *:
female:
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Hypercalcaemia (elevated calcium (ca+) level in the blood)
- Hypocalcaemia (levels of calcium in blood serum are abnormally low)
- Hypotension (abnormally low blood pressure)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Blood pressure increased
- Confusional state
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
male:
- Groin pain
- Thrombocytopenia (decrease of platelets in blood)
- Lobar pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung)
- Pneumonia
What are the common drug interactions of Septra and Temsirolimus, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Acidosis (build-up of carbon dioxide in the blood)
- Cardiac arrest
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Hypercalcaemia (elevated calcium (ca+) level in the blood)
- Hypocalcaemia (levels of calcium in blood serum are abnormally low)
- Hypotension (abnormally low blood pressure)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Blood pressure increased
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Groin pain
- Pneumonia
- Thrombocytopenia (decrease of platelets in blood)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Lobar pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung)
- Neuropathy peripheral (surface nerve damage)
What are the existing conditions these people have? *
- B Precursor Type Acute Leukaemia (lymphoid cancer): 9 people, 75.00%
- Klebsiella Infection: 6 people, 50.00%
- Pneumonia Klebsiella (pneumonia caused by bacteria klebsiella): 2 people, 16.67%
- Nausea (feeling of having an urge to vomit): 1 person, 8.33%
- Leukaemia Plasmacytic (a progressive, malignant disease of the blood-forming organs): 1 person, 8.33%
- Cough: 1 person, 8.33%
- Constipation: 1 person, 8.33%
- Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 8.33%
- B-Cell Small Lymphocytic Lymphoma (blood cancer affecting b cells): 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Septra and Temsirolimus?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Septra (10,280 reports)
- Temsirolimus (3,573 reports)
Browse all drug interactions of Septra and Temsirolimus:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Septra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Temsirolimus:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Septra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Temsirolimus and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Herrin MA, Rubinstein JC, Christison-Lagay ER, "Temsirolimus therapy and small bowel perforation in a pediatric patient with Clostridium septicum bacteremia", Journal of Pediatric Surgery Case Reports, 2015 Aug .
- Herrin MA, Rubinstein JC, Christison-Lagay ER, "Temsirolimus therapy and small bowel perforation in a pediatric patient with Clostridium septicum bacteremia", Journal of Pediatric Surgery Case Reports, 2015 Aug .
How the study uses the data?
The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim and temsirolimus (the active ingredients of Septra and Temsirolimus, respectively), and Septra and Temsirolimus (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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