Serax and Zofran drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Serax (oxazepam) and Zofran (ondansetron hydrochloride). Common drug interactions include neutropenia among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Serax and Zofran. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Serax?

Serax has active ingredients of oxazepam. It is often used in stress and anxiety. eHealthMe is studying from 1,542 Serax users. Check the latest studies of Serax.

What is Zofran?

Zofran has active ingredients of ondansetron hydrochloride. It is often used in nausea. eHealthMe is studying from 94,987 Zofran users. Check the latest studies of Zofran.

On Jul, 10, 2026

27 people who take Serax and Zofran together, and have interactions are studied.

What are the common drug interactions of Serax and Zofran, by gender? *:

female:

Neutropenia (an abnormally low number of neutrophils)
Respiratory failure (inadequate gas exchange by the respiratory system)
Premature baby
Pulmonary artery atresia (lungs artery absent)
Tricuspid valve disease (disease of heart valve)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood creatinine increased
Upper respiratory tract infection
Albumin urine present
Anaemia (lack of blood)

male:

Anaemia (lack of blood)
Depression
Pyrexia (fever)
Therapeutic response unexpected
Wheezing (a high-pitched whistling sound made while you breath)
Fatigue (feeling of tiredness)
Headache (pain in head)
Injection site pruritus (severe itching at injection site)
Injection site rash
Leukopenia (less number of white blood cells in blood)

What are the common drug interactions of Serax and Zofran, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Albumin urine present
Arthralgia (joint pain)
Blood calcium increased
Blood creatinine increased
Blood glucose increased
Blood thyroid stimulating hormone increased
Contusion (a type of hematoma of tissue in which capillaries)
Glomerular filtration rate decreased
Glycosylated haemoglobin increased
Haematocrit decreased

30-39:

Anaemia (lack of blood)
Depression
Fatigue (feeling of tiredness)
Headache (pain in head)
Injection site pruritus (severe itching at injection site)
Injection site rash
Leukopenia (less number of white blood cells in blood)
Suicidal ideation
Thrombocytopenia (decrease of platelets in blood)

40-49:

Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Depression
Dermatitis psoriasiform (large white or silver flakes on the skin)
Drug eruption (adverse drug reaction of the skin)
Endocarditis staphylococcal (an inflammation of the inner layer of the heart by staphylococcal bacterial infection)
Femoral arterial stenosis (narrowing of artery of femur bone)
Gangrene (body tissue dies)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

50-59:

Anaemia (lack of blood)
Anal fistula
Blood potassium decreased
Cardiomegaly (increased size of heart than normal)
Diarrhoea
Dysphagia (a condition in which swallowing is difficult or painful)
Epiglottic oedema (swelling and inflammation of the epiglottis)
Failure to thrive (inadequate weight gain and physical growth in children)
Feeding disorder (when children refuse to eat certain food groups)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

60+:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Neutropenia (an abnormally low number of neutrophils)
Atelectasis (partial or complete collapse of the lung)
Apnoea (suspension of external breathing)
Biliary dilatation
Blood alkaline phosphatase increased
Blood creatinine increased
Blood lactate dehydrogenase increased
Cardiac failure congestive
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)

What are the existing conditions these people have? *

Insomnia (sleeplessness): 9 people, 33.33%
Pain: 7 people, 25.93%
Postpartum Depression (depression suffered by a mother following childbirth): 6 people, 22.22%
Depression: 6 people, 22.22%
Ovarian Cancer (cancer of ovary): 4 people, 14.81%
High Blood Pressure: 4 people, 14.81%
Sleep Disorder: 3 people, 11.11%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 3 people, 11.11%
Bipolar Ii Disorder (characterized by at least one episode of hypomania and at least one episode of major depression): 3 people, 11.11%
Diarrhea: 3 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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