Serevent and Actemra drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Serevent (salmeterol xinafoate) and Actemra (tocilizumab). Common drug interactions include interstitial lung disease among females and arthralgia among males.
The phase IV clinical study analyzes what interactions people have when they take Serevent and Actemra. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.
What is Serevent?
Serevent has active ingredients of salmeterol xinafoate. It is often used in asthma. eHealthMe is studying from 15,586 Serevent users. Check the latest studies of Serevent.
What is Actemra?
Actemra has active ingredients of tocilizumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 102,759 Actemra users. Check the latest studies of Actemra.
15 people who take Serevent and Actemra together, and have interactions are studied.

What are the common drug interactions of Serevent and Actemra, by gender? *:
female:
- Interstitial lung disease
- Pneumonia
- Pulmonary embolism (blockage of the main artery of the lung)
- Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Paralysis
- Diabetes mellitus inadequate control
- Dizziness
- Dry mouth
- Headache (pain in head)
male:
- Arthralgia (joint pain)
- Blood pressure fluctuation
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cough
- Cyst (a closed sac)
- Diarrhoea
- Dizziness
- Erythema (redness of the skin)
- Exostosis (formation of new bone on the surface of a bone)
- Hyperkeratosis (thickening of the outer layer of the skin)
What are the common drug interactions of Serevent and Actemra, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Arthralgia (joint pain)
- Blood pressure fluctuation
- Dizziness
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cough
- Cyst (a closed sac)
- Diarrhoea
- Erythema (redness of the skin)
- Exostosis (formation of new bone on the surface of a bone)
- Hyperkeratosis (thickening of the outer layer of the skin)
What are the existing conditions these people have? *
- Osteoporosis (bones weak and more likely to break): 2 people, 13.33%
- Polyarthritis (arthritis which involves 5 or more joints simultaneously): 1 person, 6.67%
- Pain: 1 person, 6.67%
- Joint Pain: 1 person, 6.67%
- Dyspnea (difficult or laboured breathing): 1 person, 6.67%
- Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function): 1 person, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Serevent and Actemra?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Serevent and Actemra:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Serevent:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Actemra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Serevent and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Actemra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on salmeterol xinafoate and tocilizumab (the active ingredients of Serevent and Actemra, respectively), and Serevent and Actemra (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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