Serevent and Lotrel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Serevent (salmeterol xinafoate) and Lotrel (amlodipine besylate; benazepril hydrochloride). Common drug interactions include coronary artery disease among females and arrhythmia among males.

The phase IV clinical study analyzes what interactions people have when they take Serevent and Lotrel. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Serevent?

Serevent has active ingredients of salmeterol xinafoate. It is often used in asthma. eHealthMe is studying from 15,586 Serevent users. Check the latest studies of Serevent.

What is Lotrel?

Lotrel has active ingredients of amlodipine besylate; benazepril hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 13,571 Lotrel users. Check the latest studies of Lotrel.

On Aug, 07, 2026

35 people who take Serevent and Lotrel together, and have interactions are studied.

What are the common drug interactions of Serevent and Lotrel, by gender? *:

female:

Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Cardioactive drug level above therapeutic
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Asthenia (weakness)
Dyspnoea (difficult or laboured respiration)
Multiple injuries
Pain
Panic attack
Pneumonia
Anaemia (lack of blood)

male:

Arrhythmia (irregular heartbeat)
Renal failure chronic (long lasting kidney dysfunction)
Chest pain
Death
Dyspnoea (difficult or laboured respiration)
Flushing (the warm, red condition of human skin)
Pain in extremity
Pulmonary embolism (blockage of the main artery of the lung)
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
Sweating increased (excess sweating)

What are the common drug interactions of Serevent and Lotrel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Arrhythmia (irregular heartbeat)
Renal failure chronic (long lasting kidney dysfunction)

30-39:

n/a

40-49:

n/a

50-59:

Bronchial hyperactivity
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Dyskinesia (abnormality or impairment of voluntary movement)
Emotional disorder
Hyperlipidaemia (presence of excess lipids in the blood)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Hypoxia (low oxygen in tissues)
Masked facies (mask like facial expression, display little facial expression)
Non-cardiac chest pain

60+:

Dyspnoea (difficult or laboured respiration)
Anaemia (lack of blood)
Cardiac arrest
Cardiac failure congestive
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest pain
Chronic lymphocytic leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell))
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Contusion (a type of hematoma of tissue in which capillaries)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.57%
Back Pain: 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

Do you take Serevent and Lotrel?

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