Sertraline hydrochloride and Heparin sodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sertraline hydrochloride (sertraline hydrochloride) and Heparin sodium (heparin sodium). Common drug interactions include dehydration among females and urinary tract infection among males.

The phase IV clinical study analyzes what interactions people have when they take Sertraline hydrochloride and Heparin sodium. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Sertraline hydrochloride?

Sertraline hydrochloride has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 28,199 Sertraline hydrochloride users. Check the latest studies of Sertraline hydrochloride.

What is Heparin sodium?

Heparin sodium has active ingredients of heparin sodium. It is often used in deep venous thrombosis. eHealthMe is studying from 21,065 Heparin sodium users. Check the latest studies of Heparin sodium.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

42 people who take Sertraline hydrochloride and Heparin sodium together, and have interactions are studied.

Sertraline hydrochloride and Heparin sodium drug interactions.

What are the common drug interactions of Sertraline Hydrochloride and Heparin Sodium, by gender? *:

female:

Dehydration (dryness resulting from the removal of water)
Emotional distress
Fear
Oliguria (not enough urine)
Seasonal allergy (allergic condition due to certain season)
Abdominal pain
Adverse drug reaction
Back pain
Chronic graft versus host disease (immune cells attack the host's body cells after transplant)
Death

male:

Urinary tract infection
Asthenia (weakness)
Chest discomfort
Chest pain
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Coagulopathy (blood's ability to clot is impaired)
Dysphagia (a condition in which swallowing is difficult or painful)
Fatigue (feeling of tiredness)
Feeling cold
Haematoma (collection of blood outside the blood vessels)

What are the common drug interactions of Sertraline Hydrochloride and Heparin Sodium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Febrile neutropenia (fever with reduced white blood cells)
Sepsis (a severe blood infection that can lead to organ failure and death)
Bacteraemia (presence of bacteria in the blood)
Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

20-29:

Abdominal pain
Blood pressure fluctuation
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest pain
Coagulopathy (blood's ability to clot is impaired)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Dizziness
Dysuria (painful or difficult urination)
Fear

30-39:

Chronic graft versus host disease (immune cells attack the host's body cells after transplant)
Pulmonary embolism (blockage of the main artery of the lung)
Abdominal distension
Anaemia of chronic disease
Arthralgia (joint pain)
Cataract (clouding of the lens inside the eye)
Cough
Depressed mood
Drug intolerance (drug sensitivity)
Dysphagia (a condition in which swallowing is difficult or painful)

40-49:

Chronic kidney disease
Renal injury (kidney injury)
Abdominal pain upper
Asthenia (weakness)
Dyspnoea (difficult or laboured respiration)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypotension (abnormally low blood pressure)
Peritonitis bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial)
Pyrexia (fever)
Vomiting

50-59:

Rash pruritic (redness with itching)
Skin irritation
Urinary tract infection
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Pneumonia
Pneumonia bacterial (pneumonia associated with bacterial infection)
Abdominal pain lower
Benign prostatic hyperplasia (benign enlargement of the prostate)
Cough
Cystitis (inflammation of the wall of the bladder)

60+:

Nausea (feeling of having an urge to vomit)
Asthenia (weakness)
Urinary tract infection
Hyperkalaemia (damage to or disease of the kidney)
Chest pain
Multi-organ failure (multisystem organ failure)
Renal failure acute (rapid kidney dysfunction)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Abdominal pain
Arrhythmia (irregular heartbeat)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 16.67%
Pain: 6 people, 14.29%
Insomnia (sleeplessness): 6 people, 14.29%
Stress And Anxiety: 4 people, 9.52%
Hypersensitivity: 4 people, 9.52%
Fever: 4 people, 9.52%
Constipation: 4 people, 9.52%
Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 7.14%
Oropharyngeal Pain: 3 people, 7.14%
Itching: 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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