Sertraline and Fluoride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sertraline (sertraline hydrochloride) and Fluoride (fluoride). Common drug interactions include mean cell volume decreased among females and dehydration among males.

The phase IV clinical study analyzes what interactions people have when they take Sertraline and Fluoride. It is created by eHealthMe based on reports of 64 people who take the same drugs from the FDA, and is updated regularly.

What is Sertraline?

Sertraline has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 153,304 Sertraline users. Check the latest studies of Sertraline.

What is Fluoride?

Fluoride has active ingredients of fluoride. eHealthMe is studying from 2,301 Fluoride users. Check the latest studies of Fluoride.

On Jul, 06, 2026

64 people who take Sertraline and Fluoride together, and have interactions are studied.

Sertraline and Fluoride drug interactions.

What are the common drug interactions of Sertraline and Fluoride, by gender? *:

female:

Mean cell volume decreased (less of the average red blood cell volume)
Metrorrhagia (uterine bleeding at irregular intervals)
Micturition urgency (urgency to pass the urine)
Monocyte count decreased
Nail avulsion (trauma to the nail can cause the nail plate to be torn from the nail bed)
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
Overdose
Panic attack
Paronychia (infection in the tissues adjacent to a nail on a finger or toe)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)

male:

Dehydration (dryness resulting from the removal of water)
Nausea (feeling of having an urge to vomit)
General physical health deterioration (weak health status)
Hospitalisation
Mobility decreased (ability to move is reduced)
Mucosal inflammation (infection of mucous membrane)
Overdose
Pain
Pneumonia
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

What are the common drug interactions of Sertraline and Fluoride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Interstitial lung disease
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)

20-29:

Abdominal pain
Dyspnoea (difficult or laboured respiration)

30-39:

Drug intolerance (drug sensitivity)
Fluid overload (too much fluid in the blood)

40-49:

Colitis (inflammation of colon)
Mucosal inflammation (infection of mucous membrane)
Hyperhidrosis (abnormally increased sweating)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Pericarditis (inflammation of the pericardium)

50-59:

Pneumonia
Abasia (inability to walk)
Abdominal pain
Abdominal wall haematoma (abdominal wall blood clotting)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cardiac arrest
Cardiac murmur (an heart sound in valve abnormality)
Comminuted fracture (bone has broken into several pieces)

60+:

Urinary tract infection
Dehydration (dryness resulting from the removal of water)
Psoriasis (immune-mediated disease that affects the skin)
Renal impairment (severely reduced kidney function)
Bladder obstruction
Weight decreased
Acne (skin problems that cause pimples)
Blood pressure increased
C-reactive protein increased
Cellulitis (infection under the skin)

What are the existing conditions these people have? *

Pain: 13 people, 20.31%
Stress And Anxiety: 5 people, 7.81%
Carcinoid Tumor Of The Small Bowel: 5 people, 7.81%
Type 2 Diabetes: 4 people, 6.25%
Parkinson's Disease: 4 people, 6.25%
Multiple Myeloma (cancer of the plasma cells): 4 people, 6.25%
Hiv Infection: 4 people, 6.25%
High Blood Pressure: 4 people, 6.25%
Abdominal Discomfort: 4 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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