Sertraline and Kalbitor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sertraline (sertraline hydrochloride) and Kalbitor (ecallantide). Common drug interactions include hereditary angioedema among females and aortic dilatation among males.

The phase IV clinical study analyzes what interactions people have when they take Sertraline and Kalbitor. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Sertraline?

Sertraline has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 153,304 Sertraline users. Check the latest studies of Sertraline.

What is Kalbitor?

Kalbitor has active ingredients of ecallantide. eHealthMe is studying from 2,079 Kalbitor users. Check the latest studies of Kalbitor.

On Jul, 09, 2026

24 people who take Sertraline and Kalbitor together, and have interactions are studied.

Sertraline and Kalbitor drug interactions.

What are the common drug interactions of Sertraline and Kalbitor, by gender? *:

female:

Hereditary angioedema (recurrent episodes of severe swelling)
Drug ineffective
Fatigue (feeling of tiredness)
Pulmonary valve incompetence
Pulmonary valve stenosis (heart valve disorder in which outflow of blood from the right ventricle of the heart is obstructed at the level of the pulmonic valve)
Right ventricular hypertrophy (right ventricular enlargement)
Fall
Foot fracture
Upper limb fracture
Abdominal distension

male:

Aortic dilatation
Aortic valve incompetence
Pulmonary valve incompetence
Pulmonary valve stenosis (heart valve disorder in which outflow of blood from the right ventricle of the heart is obstructed at the level of the pulmonic valve)
Tricuspid valve incompetence (inefficient heart valve)
Vocal cord paralysis
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Cardiomegaly (increased size of heart than normal)
Coarctation of the aorta (narrowing of the part of aorta)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)

What are the common drug interactions of Sertraline and Kalbitor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Aortic dilatation
Aortic valve incompetence
Cardiomegaly (increased size of heart than normal)
Coarctation of the aorta (narrowing of the part of aorta)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Lobar pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung)
Premature baby
Pulmonary artery stenosis congenital (congenital -narrowing (stenosis) that occurs in the lung artery)
Pulmonary congestion (congestion in the lungs)

30-39:

n/a

40-49:

Drug ineffective
Pulmonary valve incompetence
Pulmonary valve stenosis (heart valve disorder in which outflow of blood from the right ventricle of the heart is obstructed at the level of the pulmonic valve)
Right ventricular hypertrophy (right ventricular enlargement)
Hereditary angioedema (recurrent episodes of severe swelling)
Sepsis (a severe blood infection that can lead to organ failure and death)
Cough
Device related infection
Hypertension (high blood pressure)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)

50-59:

Pollakiuria (abnormally frequent passage of relatively small quantities or urine)

60+:

Abdominal distension
Arthralgia (joint pain)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Vomiting
Intestinal obstruction
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Erythema (redness of the skin)
Pruritus (severe itching of the skin)
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
Skin discolouration (change of skin colour)

What are the existing conditions these people have? *

Hereditary Angioedema (recurrent episodes of severe swelling): 20 people, 83.33%
Immune System Disorder: 10 people, 41.67%
Interstitial Lung Disease: 3 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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