Sertraline and Nuplazid drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Sertraline (sertraline hydrochloride) and Nuplazid (pimavanserin tartrate). Common drug interactions include nausea among females and hallucination among males.
The phase IV clinical study analyzes what interactions people have when they take Sertraline and Nuplazid. It is created by eHealthMe based on reports of 1,479 people who take the same drugs from the FDA, and is updated regularly.
What is Sertraline?
Sertraline has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 153,304 Sertraline users. Check the latest studies of Sertraline.
What is Nuplazid?
Nuplazid has active ingredients of pimavanserin tartrate. eHealthMe is studying from 47,103 Nuplazid users. Check the latest studies of Nuplazid.
1,479 people who take Sertraline and Nuplazid together, and have interactions are studied.

What are the common drug interactions of Sertraline and Nuplazid, by gender? *
What are the common drug interactions of Sertraline and Nuplazid, by age (0-1 to 60+)? *
What are the existing conditions these people have? *
* Approximation only. Some reports may have incomplete information.
Do you take Sertraline and Nuplazid?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Sertraline (153,304 reports)
- Nuplazid (47,103 reports)
Browse all drug interactions of Sertraline and Nuplazid:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Sertraline:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Nuplazid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sertraline and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nuplazid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
- Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on sertraline hydrochloride and pimavanserin tartrate (the active ingredients of Sertraline and Nuplazid, respectively), and Sertraline and Nuplazid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Could Timolol Maleate cause Vertigo Aggravated? - 6 seconds ago
- Could Suprep Bowel Prep Kit cause Headache? - 10 seconds ago
- Could Alphagan P cause Haematochezia? - 18 seconds ago
- Could Magnesium cause Tonic Convulsion? - 25 seconds ago
- Thyroid Diseases and Fall - 34 seconds ago
- Could Metformin Hydrochloride cause Dyspnea Exacerbated? - 43 seconds ago
- Drug interactions of Abilify and Sectral - 46 seconds ago
- Feldene vs. Diclofenac Potassium, side effect and effectiveness comparison - 46 seconds ago
- Anaesthesia and Hydrocephalus - 48 seconds ago
- Could Prolia cause Pancytopenia Aggravated? - a minute ago