Sertraline and Serevent drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Sertraline (sertraline hydrochloride) and Serevent (salmeterol xinafoate). Common drug interactions include weight decreased among females and subarachnoid haemorrhage among males.
The phase IV clinical study analyzes what interactions people have when they take Sertraline and Serevent. It is created by eHealthMe based on reports of 78 people who take the same drugs from the FDA, and is updated regularly.
What is Sertraline?
Sertraline has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 153,304 Sertraline users. Check the latest studies of Sertraline.
What is Serevent?
Serevent has active ingredients of salmeterol xinafoate. It is often used in asthma. eHealthMe is studying from 15,586 Serevent users. Check the latest studies of Serevent.
78 people who take Sertraline and Serevent together, and have interactions are studied.

What are the common drug interactions of Sertraline and Serevent, by gender? *:
female:
- Weight decreased
- Cellulitis (infection under the skin)
- Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
- Drug hypersensitivity
- Dysphagia (a condition in which swallowing is difficult or painful)
- Fall
- Hallucination, auditory (perceiving sounds without auditory stimulus)
- Pain in extremity
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Pneumonia
male:
- Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Ankle fracture
- Aphonia (inability to produce voice)
- Arrhythmia (irregular heartbeat)
- Asthenia (weakness)
- Attention deficit/hyperactivity disorder
- Autonomic failure syndrome (a degenerative disease of the autonomic nervous system)
- Autonomic neuropathy (malfunction of the autonomic nervous system (ans))
What are the common drug interactions of Sertraline and Serevent, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Alopecia (absence of hair from areas of the body)
- Abortion missed (delayed or silent miscarriage)
- Aphasia (damage to the parts of the brain that control language)
- Chest pain
- Collapse (sudden functional breakdown)
- Dizziness
- Dyskinesia (abnormality or impairment of voluntary movement)
- Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
- Extrasystoles
- Eyelid function disorder
40-49:
- Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Diarrhoea
- Hallucination, auditory (perceiving sounds without auditory stimulus)
- Hypoaesthesia (reduced sense of touch or sensation)
- Nausea (feeling of having an urge to vomit)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Therapeutic response unexpected
- Tremor (trembling or shaking movements in one or more parts of your body)
- Vomiting
50-59:
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Delirium (wild excitement)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
- Epicondylitis (tennis elbow)
- Fall
- Fatigue (feeling of tiredness)
- Foot fracture
- Gastric ulcer (stomach ulcer)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
60+:
- Asthenia (weakness)
- Dyspnoea (difficult or laboured respiration)
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Rash
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Tremor (trembling or shaking movements in one or more parts of your body)
- Vomiting
- Abasia (inability to walk)
- Abdominal adhesions (inflammation of abdomen)
- Abdominal pain upper
What are the existing conditions these people have? *
- Psoriasis (immune-mediated disease that affects the skin): 9 people, 11.54%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 7.69%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 6.41%
* Approximation only. Some reports may have incomplete information.
Do you take Sertraline and Serevent?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Sertraline (153,304 reports)
- Serevent (15,586 reports)
Browse all drug interactions of Sertraline and Serevent:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Sertraline:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Serevent:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sertraline and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Serevent and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
- Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on sertraline hydrochloride and salmeterol xinafoate (the active ingredients of Sertraline and Serevent, respectively), and Sertraline and Serevent (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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