Sertraline and Trusopt drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sertraline (sertraline hydrochloride) and Trusopt (dorzolamide hydrochloride). Common drug interactions include diarrhoea among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Sertraline and Trusopt. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Sertraline?

Sertraline has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 153,304 Sertraline users. Check the latest studies of Sertraline.

What is Trusopt?

Trusopt has active ingredients of dorzolamide hydrochloride. It is often used in glaucoma. eHealthMe is studying from 3,165 Trusopt users. Check the latest studies of Trusopt.

On Jul, 16, 2026

21 people who take Sertraline and Trusopt together, and have interactions are studied.

Sertraline and Trusopt drug interactions.

What are the common drug interactions of Sertraline and Trusopt, by gender? *:

female:

Diarrhoea
Dehydration (dryness resulting from the removal of water)
Abdominal pain
Decreased appetite
Mobility decreased (ability to move is reduced)
Somnolence (a state of near-sleep, a strong desire for sleep)
Tremor (trembling or shaking movements in one or more parts of your body)
Dyspepsia (indigestion)
Acute myocardial infarction (acute heart attack)
Adverse drug reaction

male:

Death
Chronic kidney disease
Nasopharyngitis (inflammation of the nasopharynx)
Nephrogenic anaemia (anaemia due to kidney disease)
Pain
Platelet count decreased
Respiratory distress (difficulty in breathing)
Unresponsive to stimuli
Vomiting
Renal failure (kidney dysfunction)

What are the common drug interactions of Sertraline and Trusopt, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Chronic kidney disease
Death
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Nephrogenic anaemia (anaemia due to kidney disease)

60+:

Diarrhoea
Dehydration (dryness resulting from the removal of water)
Acute myocardial infarction (acute heart attack)
Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood cholesterol increased
Body height decreased
Cardiac arrest
Cardiac failure congestive

What are the existing conditions these people have? *

Stress And Anxiety: 4 people, 19.05%
Metastases To Peritoneum (cancer spreads to peritoneum): 2 people, 9.52%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 9.52%
Essential Hypertension (primary hypertension): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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