Sevoflurane and Nimbex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sevoflurane (sevoflurane) and Nimbex (cisatracurium besylate). Common drug interactions include blood pressure decreased among females and erythema among males.

The phase IV clinical study analyzes what interactions people have when they take Sevoflurane and Nimbex. It is created by eHealthMe based on reports of 76 people who take the same drugs from the FDA, and is updated regularly.

What is Sevoflurane?

Sevoflurane has active ingredients of sevoflurane. eHealthMe is studying from 9,513 Sevoflurane users. Check the latest studies of Sevoflurane.

What is Nimbex?

Nimbex has active ingredients of cisatracurium besylate. eHealthMe is studying from 1,546 Nimbex users. Check the latest studies of Nimbex.

On Jul, 09, 2026

76 people who take Sevoflurane and Nimbex together, and have interactions are studied.

Sevoflurane and Nimbex drug interactions.

What are the common drug interactions of Sevoflurane and Nimbex, by gender? *:

female:

Blood pressure decreased
Hepatocellular injury (liver injury)
Ventricular fibrillation (abnormally irregular heart rhythm)
Hypotension (abnormally low blood pressure)
Anaesthetic complication
Hypoproteinaemia (too little prolactin circulating in the blood)
Overdose
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Hyperthermia (body temperature greatly above normal)

male:

Erythema (redness of the skin)
Hypotension (abnormally low blood pressure)
Hypoxia (low oxygen in tissues)
Lymphopenia (an abnormally low level of lymphocytes in the blood)
Peripheral ischaemia (impaired circulation to an extremity)
Pityriasis (a skin disease characterized by the shedding of fine flaky scales)
Proteinuria (presence of protein in the urine)
Rales (an abnormal respiratory sound characterized by fine crackles)
Sepsis (a severe blood infection that can lead to organ failure and death)
Toxic skin eruption (skin breakdown due to toxic substance)

What are the common drug interactions of Sevoflurane and Nimbex, by age (0-1 to 60+)? *:

0-1:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Cardiac arrest
Death
Emotional distress
Fear
Hypoproteinaemia (too little prolactin circulating in the blood)
Injury
Multi-organ failure (multisystem organ failure)
Overdose

2-9:

Acidosis (build-up of carbon dioxide in the blood)
Blood pressure diastolic decreased
Cardiac arrest
Crepitations (noises are produced by the rubbing of parts one against the other)
Delayed recovery from anaesthesia
Diplopia (double vision)
General physical health deterioration (weak health status)
Hemiparesis (weakness on one side of the body)
Hypercapnia (too much smoke)
Hyperthermia malignant (disease passed down through families that causes a fast rise in body temperature (fever) and severe muscle contractions)

10-19:

Acute generalised exanthematous pustulosis (acute febrile drug eruption)
Priapism (prolonged and painful erection that can last from several hours up to a few days)

20-29:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Apnoea (suspension of external breathing)
Loss of consciousness

30-39:

Hepatocellular injury (liver injury)
Apnoea (suspension of external breathing)
Respiratory rate decreased (less breathing rate/min)
Sepsis (a severe blood infection that can lead to organ failure and death)
Atrioventricular block complete (heart block complete)
Aura
Bradycardia (abnormally slow heart action)
Depressed level of consciousness
Flushing (the warm, red condition of human skin)
Heart rate decreased

40-49:

Hypotension (abnormally low blood pressure)
Oxygen saturation decreased
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Hepatocellular injury (liver injury)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Haemophilus infection (bacterial infection by haemophilus influenzae)
Hyperthermia (body temperature greatly above normal)
Mediastinal haematoma (blood clot in mediastinum)
Pericardial haemorrhage (bleeding into the heart)
Pleural effusion (water on the lungs)

50-59:

Fear
Injury
Memory impairment
Oedema (fluid collection in tissue)
Pain
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Stress
Tachyphrenia (abnormally rapid mental activity)

60+:

Erythema (redness of the skin)
Hypotension (abnormally low blood pressure)
Pulse absent
Lymphopenia (an abnormally low level of lymphocytes in the blood)
Peripheral ischaemia (impaired circulation to an extremity)
Pityriasis (a skin disease characterized by the shedding of fine flaky scales)
Proteinuria (presence of protein in the urine)
Rales (an abnormal respiratory sound characterized by fine crackles)
Toxic skin eruption (skin breakdown due to toxic substance)
Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)

What are the existing conditions these people have? *

Anaesthesia: 26 people, 34.21%
General Anaesthesia: 16 people, 21.05%
Pain: 9 people, 11.84%
High Blood Pressure: 9 people, 11.84%
Type 2 Diabetes: 8 people, 10.53%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 8 people, 10.53%
Oesophagitis (inflammation of oesophagus): 8 people, 10.53%
Infection: 8 people, 10.53%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 8 people, 10.53%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 10.53%

* Approximation only. Some reports may have incomplete information.

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