Silodosin and Midazolam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Silodosin (silodosin) and Midazolam (midazolam). Common drug interactions include angle closure glaucoma among males.

The phase IV clinical study analyzes what interactions people have when they take Silodosin and Midazolam. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Silodosin?

Silodosin has active ingredients of silodosin. eHealthMe is studying from 3,839 Silodosin users. Check the latest studies of Silodosin.

What is Midazolam?

Midazolam has active ingredients of midazolam. eHealthMe is studying from 11,246 Midazolam users. Check the latest studies of Midazolam.



On Jul, 10, 2026

14 people who take Silodosin and Midazolam together, and have interactions are studied.

Silodosin and Midazolam drug interactions.

What are the common drug interactions of Silodosin and Midazolam, by gender? *:

female:

n/a

male:

  1. Angle closure glaucoma (term used for several ocular diseases that ultimately result in increased intraocular pressure (iop) and decreased visual acuity)
  2. Colitis ulcerative (inflammation of colon with ulcer)
  3. Vomiting
  4. Arteriosclerotic retinopathy (retinal disease caused by arteriosclerosis)
  5. Confusional state
  6. Conjunctival hyperaemia (congestion of conjunctival vessels)
  7. Corneal oedema (corneal swelling)
  8. Glaucoma (increased fluid pressure in the eye with vision loss)
  9. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  10. Intraocular pressure increased

What are the common drug interactions of Silodosin and Midazolam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Angle closure glaucoma (term used for several ocular diseases that ultimately result in increased intraocular pressure (iop) and decreased visual acuity)
  2. Arteriosclerotic retinopathy (retinal disease caused by arteriosclerosis)
  3. Conjunctival hyperaemia (congestion of conjunctival vessels)
  4. Corneal oedema (corneal swelling)
  5. Glaucoma (increased fluid pressure in the eye with vision loss)
  6. Intraocular pressure increased
  7. Iritis (painful inflammation of the iris of the eye)
  8. Mydriasis (a dilation of the pupil)
  9. Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
  10. Recession of chamber angle of eye (glaucoma that is due to damage to the anterior chamber of the eye)

60+:

  1. Colitis ulcerative (inflammation of colon with ulcer)
  2. Blood fibrinogen decreased
  3. Confusional state
  4. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  5. Somnolence (a state of near-sleep, a strong desire for sleep)
  6. Blood pressure decreased
  7. Disease progression
  8. Fibrin d dimer increased
  9. Fibrin degradation products increased
  10. Gastric haemorrhage (bleeding stomach)

What are the existing conditions these people have? *

  1. Fungal Infection: 6 people, 42.86%
  2. Sedation: 6 people, 42.86%
  3. Bacterial Infection: 6 people, 42.86%
  4. Increased Viscosity Of Bronchial Secretion: 5 people, 35.71%
  5. Urinary Retention (the inability to completely or partially empty the bladder): 4 people, 28.57%
  6. Ards (Acute Respiratory Distress Syndrome) (sudden failure of the respiratory (breathing) system): 3 people, 21.43%
  7. High Blood Pressure: 3 people, 21.43%
  8. Urinary Incontinence (inability to control the flow of urine and involuntary urination): 2 people, 14.29%
  9. Infection: 2 people, 14.29%
  10. Productive Cough: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Silodosin and Midazolam?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Silodosin and Midazolam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Silodosin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Midazolam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Silodosin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Midazolam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on silodosin and midazolam (the active ingredients of Silodosin and Midazolam, respectively), and Silodosin and Midazolam (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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