Silvadene and Boniva drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Silvadene (silver sulfadiazine) and Boniva (ibandronate sodium). Common drug interactions include renal failure acute among females.

The phase IV clinical study analyzes what interactions people have when they take Silvadene and Boniva. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Silvadene?

Silvadene has active ingredients of silver sulfadiazine. eHealthMe is studying from 1,161 Silvadene users. Check the latest studies of Silvadene.

What is Boniva?

Boniva has active ingredients of ibandronate sodium. It is often used in osteoporosis. eHealthMe is studying from 27,340 Boniva users. Check the latest studies of Boniva.

On Jul, 13, 2026

12 people who take Silvadene and Boniva together, and have interactions are studied.

What are the common drug interactions of Silvadene and Boniva, by gender? *:

female:

Renal failure acute (rapid kidney dysfunction)
Autoimmune hepatitis
Hypertension (high blood pressure)
Proteinuria (presence of protein in the urine)
Chronic left ventricular failure (long lasting functional impairment of left ventricle of heart)
Dry eye (lack of adequate tears)
Headache (pain in head)
Hypergammaglobulinaemia benign monoclonal (elevated levels of gamma globulin)
Clostridium difficile toxin test positive
Kidney fibrosis (excess fibrous connective tissue in kidney)

male:

n/a

What are the common drug interactions of Silvadene and Boniva, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Focal segmental glomerulosclerosis (scar tissue that forms in parts of the kidney called glomeruli)
Transaminases increased
Clostridial infection (infectious conditions by clostridium bacteria)
Blood creatinine increased
Glomerulosclerosis (a hardening of the glomerulus in the kidney)
Hypertension (high blood pressure)
Proteinuria (presence of protein in the urine)
Hypergammaglobulinaemia benign monoclonal (elevated levels of gamma globulin)
Clostridium difficile toxin test positive

60+:

Abdominal discomfort
Abdominal pain upper
Arterial disorder
Asthenia (weakness)
Back pain
Balance disorder
Bile duct obstruction (blockage in the tubes that carry bile from the liver to the gallbladder)
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Bone neoplasm (tumour of bone)
Bone pain

What are the existing conditions these people have? *

Sepsis (a severe blood infection that can lead to organ failure and death): 8 people, 66.67%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 8 people, 66.67%
Localised Infection (infection at the single location): 8 people, 66.67%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 7 people, 58.33%
High Blood Pressure: 7 people, 58.33%
Asthma: 4 people, 33.33%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 25.00%
Post Procedural Infection: 2 people, 16.67%
Infection: 1 person, 8.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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