Silymarin and Actrapid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Silymarin (milk thistle) and Actrapid (insulin). Common drug interactions include anaemia among females and delirium among males.

The phase IV clinical study analyzes what interactions people have when they take Silymarin and Actrapid. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Silymarin?

Silymarin has active ingredients of milk thistle. eHealthMe is studying from 793 Silymarin users. Check the latest studies of Silymarin.

What is Actrapid?

Actrapid has active ingredients of insulin. eHealthMe is studying from 4,864 Actrapid users. Check the latest studies of Actrapid.

On Jul, 31, 2026

12 people who take Silymarin and Actrapid together, and have interactions are studied.

Silymarin and Actrapid drug interactions.

What are the common drug interactions of Silymarin and Actrapid, by gender? *:

female:

Anaemia (lack of blood)
Cytomegalovirus hepatitis (virus infection of liver)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Pyrexia (fever)
Respiratory failure (inadequate gas exchange by the respiratory system)
Blood glucose fluctuation
Blood glucose increased
Coma hepatic (accumulation in the bloodstream of toxic substances that are normally removed by the liver leads coma)

male:

Delirium (wild excitement)
Depressed level of consciousness
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Colitis (inflammation of colon)
Dyspnoea (difficult or laboured respiration)
Gangrene (body tissue dies)
Haematuria (presence of blood in urine)
Limb injury
Pneumonia

What are the common drug interactions of Silymarin and Actrapid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Anaemia (lack of blood)
Cytomegalovirus hepatitis (virus infection of liver)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Pyrexia (fever)
Respiratory failure (inadequate gas exchange by the respiratory system)

60+:

Delirium (wild excitement)
Depressed level of consciousness
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Colitis (inflammation of colon)
Dyspnoea (difficult or laboured respiration)
Gangrene (body tissue dies)
Haematuria (presence of blood in urine)
Limb injury
Pneumonia

What are the existing conditions these people have? *

High Blood Pressure: 8 people, 66.67%
Diabetes: 8 people, 66.67%
Hepatic Steatosis (fatty liver disease): 6 people, 50.00%
Gout (uric acid crystals building up in the body): 6 people, 50.00%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 6 people, 50.00%
Allergies: 5 people, 41.67%
Diarrhea: 3 people, 25.00%
Dermatitis Diaper (diaper rash is a common form of inflamed skin): 2 people, 16.67%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 2 people, 16.67%
Fever: 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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