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Simcor and Compazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Simcor (niacin; simvastatin) and Compazine (prochlorperazine maleate). Common drug interactions include drug hypersensitivity among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Simcor and Compazine. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Simcor?

Simcor has active ingredients of niacin; simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 11,604 Simcor users. Check the latest studies of Simcor.

What is Compazine?

Compazine has active ingredients of prochlorperazine maleate. It is often used in indigestion. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.

On Jul, 20, 2026

11 people who take Simcor and Compazine together, and have interactions are studied.

Simcor and Compazine drug interactions.

What are the common drug interactions of Simcor and Compazine, by gender? *:

female:

  1. Drug hypersensitivity
  2. Full blood count decreased

male:

  1. Asthenia (weakness)
  2. Autoimmune hepatitis
  3. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  4. Hyperglycaemia (high blood sugar)
  5. Transaminases increased

What are the common drug interactions of Simcor and Compazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Drug hypersensitivity

50-59:

n/a

60+:

  1. Asthenia (weakness)
  2. Autoimmune hepatitis
  3. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  4. Hyperglycaemia (high blood sugar)
  5. Transaminases increased

What are the existing conditions these people have? *

  1. Tumor: 8 people, 72.73%
  2. Pain: 8 people, 72.73%
  3. Nausea (feeling of having an urge to vomit): 8 people, 72.73%
  4. Constipation: 8 people, 72.73%
  5. Back Pain: 8 people, 72.73%
  6. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 8 people, 72.73%
  7. Oedema Peripheral (superficial swelling): 7 people, 63.64%
  8. Aspartate Aminotransferase Increased: 6 people, 54.55%
  9. Alanine Aminotransferase Increased: 6 people, 54.55%
  10. Hyperglycemia (high blood sugar): 4 people, 36.36%

* Approximation only. Some reports may have incomplete information.

Do you take Simcor and Compazine?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Simcor and Compazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Simcor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Compazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Simcor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Compazine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on niacin; simvastatin and prochlorperazine maleate (the active ingredients of Simcor and Compazine, respectively), and Simcor and Compazine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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