Simcor and Digoxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Simcor (niacin; simvastatin) and Digoxin (digoxin). Common drug interactions include withdrawal syndrome among females and flushing among males.

The phase IV clinical study analyzes what interactions people have when they take Simcor and Digoxin. It is created by eHealthMe based on reports of 99 people who take the same drugs from the FDA, and is updated regularly.

What is Simcor?

Simcor has active ingredients of niacin; simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 11,604 Simcor users. Check the latest studies of Simcor.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.

On Jul, 14, 2026

99 people who take Simcor and Digoxin together, and have interactions are studied.

What are the common drug interactions of Simcor and Digoxin, by gender? *:

female:

Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Erythema (redness of the skin)
Hot flush (sudden feelings of heat)
Muscle spasms (muscle contraction)
Feeling hot
Asthenia (weakness)
Burning sensation
Cardiac failure congestive
Drug ineffective
Dyspnoea (difficult or laboured respiration)

male:

Flushing (the warm, red condition of human skin)
Feeling hot
Mallory-weiss syndrome (gastro-oesophageal laceration syndrome refers to bleeding from tears)
Nausea (feeling of having an urge to vomit)
Diarrhoea
Muscle spasms (muscle contraction)
Skin burning sensation
Dizziness
Dyspepsia (indigestion)
Dyspnoea (difficult or laboured respiration)

What are the common drug interactions of Simcor and Digoxin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Flushing (the warm, red condition of human skin)
Nausea (feeling of having an urge to vomit)
Muscle spasms (muscle contraction)

50-59:

Swelling
Flushing (the warm, red condition of human skin)
Dizziness
Feeling hot
Blood glucose increased
Burning sensation
Skin burning sensation

60+:

Flushing (the warm, red condition of human skin)
Back pain
Erythema (redness of the skin)
Asthenia (weakness)
Dizziness
Hot flush (sudden feelings of heat)
Hyperhidrosis (abnormally increased sweating)
Mallory-weiss syndrome (gastro-oesophageal laceration syndrome refers to bleeding from tears)
Myalgia (muscle pain)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

What are the existing conditions these people have? *

High Density Lipoprotein Decreased: 19 people, 19.19%
Low Density Lipoprotein Increased (cholesterol increased in blood): 10 people, 10.10%
Neuropathy Peripheral (surface nerve damage): 6 people, 6.06%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 5 people, 5.05%
Macular Degeneration (painless eye condition that leads to the gradual loss of central vision): 5 people, 5.05%
High Blood Pressure: 5 people, 5.05%

* Approximation only. Some reports may have incomplete information.

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