Simcor and Gemfibrozil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Simcor (niacin; simvastatin) and Gemfibrozil (gemfibrozil). Common drug interactions include pruritus among females and flushing among males.

The phase IV clinical study analyzes what interactions people have when they take Simcor and Gemfibrozil. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Simcor?

Simcor has active ingredients of niacin; simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 11,604 Simcor users. Check the latest studies of Simcor.

What is Gemfibrozil?

Gemfibrozil has active ingredients of gemfibrozil. It is often used in high blood cholesterol. eHealthMe is studying from 18,213 Gemfibrozil users. Check the latest studies of Gemfibrozil.

On Jul, 10, 2026

33 people who take Simcor and Gemfibrozil together, and have interactions are studied.

Simcor and Gemfibrozil drug interactions.

What are the common drug interactions of Simcor and Gemfibrozil, by gender? *:

female:

Pruritus (severe itching of the skin)
Flushing (the warm, red condition of human skin)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Erythema (redness of the skin)
Burning sensation
Dizziness
Feeling hot
Gait disturbance
Hyperhidrosis (abnormally increased sweating)

male:

Flushing (the warm, red condition of human skin)
Feeling hot
Abdominal distension
Blood glucose increased
Chronic kidney disease
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Decreased appetite
Eye pain
Lacrimation increased
Muscle spasms (muscle contraction)

What are the common drug interactions of Simcor and Gemfibrozil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Constipation
Renal failure (kidney dysfunction)

50-59:

Flushing (the warm, red condition of human skin)
Feeling hot
Gait disturbance
Hyperhidrosis (abnormally increased sweating)
Hypoaesthesia (reduced sense of touch or sensation)
Oedema peripheral (superficial swelling)
Oral disorder (mouth disease)
Skin burning sensation

60+:

Flushing (the warm, red condition of human skin)
Headache (pain in head)
Dizziness
Erythema (redness of the skin)
Eye pain
Lacrimation increased
Nausea (feeling of having an urge to vomit)
Rash papular (redness with papule)
Renal oncocytoma (a tumour of the kidney made up of oncocytes, a special kind of cell)
Vertigo positional

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 12.12%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 9.09%
High Blood Pressure: 3 people, 9.09%
Urinary Tract Infection: 2 people, 6.06%
Type 2 Diabetes: 2 people, 6.06%
Rickets (softening of bones): 2 people, 6.06%
Neuropathy Peripheral (surface nerve damage): 2 people, 6.06%
Gastric Disorder (disease of stomach): 2 people, 6.06%
Dyslipidaemia (abnormal amount of lipids): 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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