Simcor and Nabumetone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Simcor (niacin; simvastatin) and Nabumetone (nabumetone). Common drug interactions include flushing among females and chest discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Simcor and Nabumetone. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Simcor?

Simcor has active ingredients of niacin; simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 11,604 Simcor users. Check the latest studies of Simcor.

What is Nabumetone?

Nabumetone has active ingredients of nabumetone. It is often used in arthritis. eHealthMe is studying from 9,554 Nabumetone users. Check the latest studies of Nabumetone.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

14 people who take Simcor and Nabumetone together, and have interactions are studied.

Simcor and Nabumetone drug interactions.

What are the common drug interactions of Simcor and Nabumetone, by gender? *:

female:

Flushing (the warm, red condition of human skin)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Headache (pain in head)
Pruritus (severe itching of the skin)
Feeling hot
Blood glucose increased
Diarrhoea
Generalised erythema (redness of the skin all over the body)
Muscle spasms (muscle contraction)
Urticaria (rash of round, red welts on the skin that itch intensely)

male:

Chest discomfort
Cough
Respiratory tract congestion (blockage on respiratory system)
Sinus congestion (blockage of sinus)
Wheezing (a high-pitched whistling sound made while you breath)
Dizziness
Dyspnoea (difficult or laboured respiration)
Feeling hot
Feeling of body temperature change
Flushing (the warm, red condition of human skin)

What are the common drug interactions of Simcor and Nabumetone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chest discomfort
Cough
Feeling hot
Flushing (the warm, red condition of human skin)
Hyperhidrosis (abnormally increased sweating)
Respiratory tract congestion (blockage on respiratory system)
Sinus congestion (blockage of sinus)
Wheezing (a high-pitched whistling sound made while you breath)

50-59:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pruritus (severe itching of the skin)
Rash
Rash pruritic (redness with itching)
Erythema (redness of the skin)
Feeling hot
Flushing (the warm, red condition of human skin)

60+:

Diarrhoea
Dizziness
Dyspnoea (difficult or laboured respiration)
Feeling hot
Feeling of body temperature change
Muscular weakness (muscle weakness)
Pruritus (severe itching of the skin)

What are the existing conditions these people have? *

Low Density Lipoprotein Increased (cholesterol increased in blood): 4 people, 28.57%
High Density Lipoprotein Decreased: 3 people, 21.43%
High Blood Pressure: 2 people, 14.29%
Skin Blushing/flushing (a sudden reddening of the face, neck): 1 person, 7.14%
Joint Pain: 1 person, 7.14%
Inflammation: 1 person, 7.14%
Heart Disease: 1 person, 7.14%
Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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