Simethicone and Aggrenox drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Simethicone (simethicone) and Aggrenox (aspirin; dipyridamole). Common drug interactions include hypocalcaemia among females and gastrointestinal haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Simethicone and Aggrenox. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Simethicone?

Simethicone has active ingredients of simethicone. It is often used in gas. eHealthMe is studying from 6,762 Simethicone users. Check the latest studies of Simethicone.

What is Aggrenox?

Aggrenox has active ingredients of aspirin; dipyridamole. It is often used in stroke. eHealthMe is studying from 7,654 Aggrenox users. Check the latest studies of Aggrenox.

On Jul, 21, 2026

22 people who take Simethicone and Aggrenox together, and have interactions are studied.

Simethicone and Aggrenox drug interactions.

What are the common drug interactions of Simethicone and Aggrenox, by gender? *:

female:

Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Blood creatinine increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cough
Death
Dehydration (dryness resulting from the removal of water)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Intracranial aneurysm (bulging, weak area in the wall of a cranial artery)
Polyuria (production of too much dilute urine)
Pyelonephritis (inflammation of kidney caused by bacteria)

male:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Anorectal discomfort
Anxiety
Blood pressure increased
Constipation
Decreased interest
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Irritability
Mood altered (changes in mood)

What are the common drug interactions of Simethicone and Aggrenox, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Anorectal discomfort
Asthenia (weakness)
Diarrhoea
Flatulence (flatus expelled through the anus)
Insomnia (sleeplessness)
Nausea (feeling of having an urge to vomit)
Weight decreased
Adverse event
Anger
Anxiety

60+:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Tetany (involuntary contraction of muscles)
Anaemia (lack of blood)
Blood creatine phosphokinase increased
Chest pain
Circulatory collapse
Cystitis (inflammation of the wall of the bladder)
Death
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

What are the existing conditions these people have? *

Back Pain: 13 people, 59.09%
High Blood Pressure: 13 people, 59.09%
Joint Pain: 11 people, 50.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 50.00%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 11 people, 50.00%
Hypoparathyroidism (inadequate secretion of parathyroid hormone resulting in abnormally low levels of calcium in the blood): 11 people, 50.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 11 people, 50.00%
Incontinence (lack of moderation or self-control): 11 people, 50.00%
Indigestion: 11 people, 50.00%
Cough: 11 people, 50.00%

* Approximation only. Some reports may have incomplete information.

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