Simponi and Botox drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Simponi (golimumab) and Botox (botulinum toxin type a). Common drug interactions include arthralgia among females and insomnia among males.
The phase IV clinical study analyzes what interactions people have when they take Simponi and Botox. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.
What is Simponi?
Simponi has active ingredients of golimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 86,328 Simponi users. Check the latest studies of Simponi.
What is Botox?
Botox has active ingredients of botulinum toxin type a. It is often used in migraine. eHealthMe is studying from 70,513 Botox users. Check the latest studies of Botox.
22 people who take Simponi and Botox together, and have interactions are studied.

What are the common drug interactions of Simponi and Botox, by gender? *:
female:
- Arthralgia (joint pain)
- Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
- Upper respiratory tract infection
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Drug hypersensitivity
- Alopecia (absence of hair from areas of the body)
- Seborrhoeic dermatitis (a common, inflammatory skin condition that causes flaky, white to yellowish scales to form on oily areas such as the scalp)
- Brain death
- Burning sensation
- Cerebral haemorrhage (bleeding within the brain)
male:
- Insomnia (sleeplessness)
What are the common drug interactions of Simponi and Botox, by age (0-1 to 60+)? *:
0-1:
- Drug hypersensitivity
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Cubital tunnel syndrome (a condition brought on by increased pressure on the ulnar nerve at the elbow)
- Drug ineffective
- Procedural pain
40-49:
- Alopecia (absence of hair from areas of the body)
- Seborrhoeic dermatitis (a common, inflammatory skin condition that causes flaky, white to yellowish scales to form on oily areas such as the scalp)
- Drug hypersensitivity
- Muscle spasms (muscle contraction)
50-59:
- Brain death
- Cerebral haemorrhage (bleeding within the brain)
- Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
60+:
- Anaphylactic reaction (serious allergic reaction)
- Arthralgia (joint pain)
- Upper respiratory tract infection
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Dizziness
- Dystonia (abnormal muscle tone)
- Fatigue (feeling of tiredness)
- Insomnia (sleeplessness)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Stress
What are the existing conditions these people have? *
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 12 people, 54.55%
- Ankylosing Spondylitis (type of arthritis affecting the spine): 3 people, 13.64%
- Movement - Uncontrolled Or Slow: 2 people, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Simponi and Botox?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Simponi and Botox:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Simponi:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Botox:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Simponi and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Botox and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Azuma N, Matsui K, Hashimoto N, Yoshikawa T, Sano H, "Successful Switch to Golimumab for Eosinophilia and Skin Symptoms Related to Multiple Biologics in a Patient with Rheumatoid Arthritis", Internal Medicine, 2017 Jun .
- Azuma N, Matsui K, Hashimoto N, Yoshikawa T, Sano H, "Successful Switch to Golimumab for Eosinophilia and Skin Symptoms Related to Multiple Biologics in a Patient with Rheumatoid Arthritis", Internal Medicine, 2017 Jun .
How the study uses the data?
The study uses data from the FDA. It is based on golimumab and botulinum toxin type a (the active ingredients of Simponi and Botox, respectively), and Simponi and Botox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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