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Simponi and Edetate disodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Simponi (golimumab) and Edetate disodium (edetate disodium). Common drug interactions include arthralgia among females.

The phase IV clinical study analyzes what interactions people have when they take Simponi and Edetate disodium. It is created by eHealthMe based on reports of 82 people who take the same drugs from the FDA, and is updated regularly.

What is Simponi?

Simponi has active ingredients of golimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 86,328 Simponi users. Check the latest studies of Simponi.

What is Edetate disodium?

Edetate disodium has active ingredients of edetate disodium. eHealthMe is studying from 136 Edetate disodium users. Check the latest studies of Edetate disodium.

On Jul, 18, 2026

82 people who take Simponi and Edetate disodium together, and have interactions are studied.

Simponi and Edetate disodium drug interactions.

What are the common drug interactions of Simponi and Edetate Disodium, by gender? *:

female:

  1. Arthralgia (joint pain)
  2. Arthropathy
  3. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  4. Neoplasm malignant (cancer tumour)
  5. Pain in extremity
  6. Pulmonary toxicity (side effects on the lungs)
  7. Joint swelling
  8. Joint stiffness
  9. Peripheral swelling
  10. Inflammation

male:

n/a

What are the common drug interactions of Simponi and Edetate Disodium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Pruritus (severe itching of the skin)
  2. Quality of life decreased
  3. Rash
  4. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  5. Rash pruritic (redness with itching)
  6. Red blood cell count decreased
  7. Rheumatoid nodule (a local swelling or tissue lump with rheumatoid disease)
  8. Scleritis (inflammation of sclera)
  9. Skin ulcer
  10. Swelling

50-59:

n/a

60+:

  1. Arthralgia (joint pain)
  2. Arthropathy
  3. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  4. Gastrointestinal toxicity (damage to digestive tract by any substance)
  5. Hepatotoxicity (chemical-driven liver damage)
  6. Hypersensitivity
  7. Ill-defined disorder
  8. Impaired healing
  9. Infection
  10. Irritable bowel syndrome

What are the existing conditions these people have? *

  1. Fibromyalgia (a long-term condition which causes pain all over the body): 6 people, 7.32%
  2. Back Pain: 5 people, 6.10%

* Approximation only. Some reports may have incomplete information.

Do you take Simponi and Edetate disodium?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Simponi and Edetate disodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Simponi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Edetate disodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Simponi and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Edetate disodium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on golimumab and edetate disodium (the active ingredients of Simponi and Edetate disodium, respectively), and Simponi and Edetate disodium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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