Simponi and Pyridoxine hydrochloride drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Simponi (golimumab) and Pyridoxine hydrochloride (pyridoxine hydrochloride). Common drug interactions include alopecia among females.
The phase IV clinical study analyzes what interactions people have when they take Simponi and Pyridoxine hydrochloride. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Simponi?
Simponi has active ingredients of golimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 86,328 Simponi users. Check the latest studies of Simponi.
What is Pyridoxine hydrochloride?
Pyridoxine hydrochloride has active ingredients of pyridoxine hydrochloride. eHealthMe is studying from 1,867 Pyridoxine hydrochloride users. Check the latest studies of Pyridoxine hydrochloride.
16 people who take Simponi and Pyridoxine hydrochloride together, and have interactions are studied.

What are the common drug interactions of Simponi and Pyridoxine Hydrochloride, by gender? *:
female:
- Alopecia (absence of hair from areas of the body)
- Abdominal discomfort
- Oedema (fluid collection in tissue)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Pyrexia (fever)
- Rheumatoid factor positive
- Stomatitis (inflammation of mucous membrane of mouth)
- Abdominal pain upper
- Arthralgia (joint pain)
- Asthenia (weakness)
male:
n/a
What are the common drug interactions of Simponi and Pyridoxine Hydrochloride, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Alopecia (absence of hair from areas of the body)
- Rheumatoid factor positive
- Stomatitis (inflammation of mucous membrane of mouth)
- Abdominal pain upper
- Asthenia (weakness)
- Blood cholesterol increased
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Confusional state
- Dizziness
- Dry mouth
50-59:
n/a
60+:
- Pulmonary tuberculosis (lungs tuberculosis)
What are the existing conditions these people have? *
- Stress And Anxiety: 4 people, 25.00%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 25.00%
- Psoriasis (immune-mediated disease that affects the skin): 3 people, 18.75%
- Indigestion: 3 people, 18.75%
- Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 12.50%
- Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly): 1 person, 6.25%
- Migraine (headache): 1 person, 6.25%
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Simponi and Pyridoxine hydrochloride?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Simponi (86,328 reports)
- Pyridoxine hydrochloride (1,867 reports)
Browse all drug interactions of Simponi and Pyridoxine hydrochloride:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Simponi:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Pyridoxine hydrochloride:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Simponi and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pyridoxine hydrochloride and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Azuma N, Matsui K, Hashimoto N, Yoshikawa T, Sano H, "Successful Switch to Golimumab for Eosinophilia and Skin Symptoms Related to Multiple Biologics in a Patient with Rheumatoid Arthritis", Internal Medicine, 2017 Jun .
- Azuma N, Matsui K, Hashimoto N, Yoshikawa T, Sano H, "Successful Switch to Golimumab for Eosinophilia and Skin Symptoms Related to Multiple Biologics in a Patient with Rheumatoid Arthritis", Internal Medicine, 2017 Jun .
How the study uses the data?
The study uses data from the FDA. It is based on golimumab and pyridoxine hydrochloride (the active ingredients of Simponi and Pyridoxine hydrochloride, respectively), and Simponi and Pyridoxine hydrochloride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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