Simponi and Triprolidine hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Simponi (golimumab) and Triprolidine hydrochloride (triprolidine hydrochloride). Common drug interactions include pyrexia among females.

The phase IV clinical study analyzes what interactions people have when they take Simponi and Triprolidine hydrochloride. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Simponi?

Simponi has active ingredients of golimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 86,328 Simponi users. Check the latest studies of Simponi.

What is Triprolidine hydrochloride?

Triprolidine hydrochloride has active ingredients of triprolidine hydrochloride. eHealthMe is studying from 64 Triprolidine hydrochloride users. Check the latest studies of Triprolidine hydrochloride.



On Jul, 09, 2026

42 people who take Simponi and Triprolidine hydrochloride together, and have interactions are studied.

Simponi and Triprolidine hydrochloride drug interactions.

What are the common drug interactions of Simponi and Triprolidine Hydrochloride, by gender? *:

female:

  1. Pyrexia (fever)
  2. Sinusitis (inflammation of sinus)
  3. Mobility decreased (ability to move is reduced)
  4. Oedema (fluid collection in tissue)
  5. Stomatitis (inflammation of mucous membrane of mouth)
  6. Insomnia (sleeplessness)
  7. Gait disturbance
  8. Nausea (feeling of having an urge to vomit)
  9. Dyspepsia (indigestion)
  10. Pain in extremity

male:

n/a

What are the common drug interactions of Simponi and Triprolidine Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal discomfort
  2. Alopecia (absence of hair from areas of the body)
  3. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
  4. Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
  5. Ear infection
  6. Exostosis (formation of new bone on the surface of a bone)
  7. Foot deformity (functional disability of foot)
  8. Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
  9. Joint dislocation (a joint position is changed from normal position)
  10. Laryngitis (inflammation of the larynx)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 39 people, 92.86%
  2. Psoriasis (immune-mediated disease that affects the skin): 35 people, 83.33%
  3. Arthritis (form of joint disorder that involves inflammation of one or more joints): 23 people, 54.76%
  4. Stress And Anxiety: 20 people, 47.62%
  5. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 7 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Simponi and Triprolidine hydrochloride?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Simponi and Triprolidine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Simponi:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Triprolidine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Simponi and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Triprolidine hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on golimumab and triprolidine hydrochloride (the active ingredients of Simponi and Triprolidine hydrochloride, respectively), and Simponi and Triprolidine hydrochloride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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