Sinemet cr and Oxycodone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sinemet cr (carbidopa; levodopa) and Oxycodone (oxycodone hydrochloride). Common drug interactions include anaemia among females and memory impairment among males.

The phase IV clinical study analyzes what interactions people have when they take Sinemet cr and Oxycodone. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Sinemet cr?

Sinemet cr has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 2,852 Sinemet cr users. Check the latest studies of Sinemet cr.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

On Jul, 18, 2026

18 people who take Sinemet cr and Oxycodone together, and have interactions are studied.

Sinemet cr and Oxycodone drug interactions.

What are the common drug interactions of Sinemet Cr and Oxycodone, by gender? *:

female:

Anaemia (lack of blood)
Cardiac failure congestive
Death
Gait disturbance
Heart rate decreased
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Vomiting

male:

Memory impairment
Weight increased
Fibroma (tumours that are composed of fibrous or connective tissue)
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Hyperkinesia (higher than normal levels of potassium in the circulating blood; associated with kidney failure or sometimes with the use of diuretic drugs)
Hypoaesthesia (reduced sense of touch or sensation)
Muscle rigidity (muscle stiffness)
Nerve compression
On and off phenomenon
Pain in extremity

What are the common drug interactions of Sinemet Cr and Oxycodone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Memory impairment
Mobility decreased (ability to move is reduced)
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Hyperkinesia (higher than normal levels of potassium in the circulating blood; associated with kidney failure or sometimes with the use of diuretic drugs)
Hypoaesthesia (reduced sense of touch or sensation)
Muscle rigidity (muscle stiffness)
Nerve compression
On and off phenomenon
Pain in extremity
Somnolence (a state of near-sleep, a strong desire for sleep)

What are the existing conditions these people have? *

Abnormal Faeces (abnormal stool): 7 people, 38.89%
Stress And Anxiety: 4 people, 22.22%
High Blood Pressure: 4 people, 22.22%
Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 22.22%
Joint Pain: 4 people, 22.22%
Tendonitis (a condition that causes pain and swelling of tendons): 3 people, 16.67%
High Blood Cholesterol: 3 people, 16.67%
Sleep Disorder: 3 people, 16.67%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 16.67%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 3 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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