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Sinemet cr and Plavix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sinemet cr (carbidopa; levodopa) and Plavix (clopidogrel bisulfate). Common drug interactions include tendon disorder among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Sinemet cr and Plavix. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Sinemet cr?

Sinemet cr has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 2,852 Sinemet cr users. Check the latest studies of Sinemet cr.

What is Plavix?

Plavix has active ingredients of clopidogrel bisulfate. It is often used in stent. eHealthMe is studying from 151,178 Plavix users. Check the latest studies of Plavix.

On Jul, 10, 2026

45 people who take Sinemet cr and Plavix together, and have interactions are studied.

Sinemet cr and Plavix drug interactions.

What are the common drug interactions of Sinemet Cr and Plavix, by gender? *:

female:

  1. Tendon disorder (disease of tendon)
  2. Tendon pain
  3. Urinary tract infection
  4. Dizziness
  5. Dehydration (dryness resulting from the removal of water)
  6. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  7. Visual impairment
  8. Vomiting
  9. Insomnia (sleeplessness)
  10. Constipation

male:

  1. Death
  2. Hallucination (an experience involving the perception of something not present)
  3. Difficulty in walking
  4. Drooling (drop saliva uncontrollably from the mouth)
  5. Dyskinesia (abnormality or impairment of voluntary movement)
  6. Gait disturbance
  7. Hallucination, visual (seeing things that aren't there)
  8. Hearing impaired
  9. Loss of consciousness
  10. Nightmare (unpleasant dream)

What are the common drug interactions of Sinemet Cr and Plavix, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Tremor (trembling or shaking movements in one or more parts of your body)

60+:

  1. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  2. Dizziness
  3. Constipation
  4. Dizziness postural
  5. Dyskinesia (abnormality or impairment of voluntary movement)
  6. Hypotension (abnormally low blood pressure)
  7. Somnolence (a state of near-sleep, a strong desire for sleep)
  8. Abnormal behaviour
  9. Aggression
  10. Anger

What are the existing conditions these people have? *

  1. Hallucinations (sensations that appear real but are created by your mind): 4 people, 8.89%
  2. Delusion (a false belief or opinion): 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Sinemet cr and Plavix?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Sinemet cr and Plavix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sinemet cr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Plavix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sinemet cr and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Plavix and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on carbidopa; levodopa and clopidogrel bisulfate (the active ingredients of Sinemet cr and Plavix, respectively), and Sinemet cr and Plavix (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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