Sinemet and Aubagio drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sinemet (carbidopa; levodopa) and Aubagio (teriflunomide). Common drug interactions include alopecia among females and surgery among males.

The phase IV clinical study analyzes what interactions people have when they take Sinemet and Aubagio. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Sinemet?

Sinemet has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 29,601 Sinemet users. Check the latest studies of Sinemet.

What is Aubagio?

Aubagio has active ingredients of teriflunomide. It is often used in multiple sclerosis. eHealthMe is studying from 50,041 Aubagio users. Check the latest studies of Aubagio.

On Jul, 10, 2026

18 people who take Sinemet and Aubagio together, and have interactions are studied.

What are the common drug interactions of Sinemet and Aubagio, by gender? *:

female:

Alopecia (absence of hair from areas of the body)
Nasopharyngitis (inflammation of the nasopharynx)
Deafness
Depressed mood
Dry throat
Dysstasia (difficulty in standing)
Gait disturbance
Peroneal nerve palsy
Rash erythematous (redness of the skin)
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)

male:

Surgery
Anxiety
Cartilage atrophy (cartilage extra growth)
Device dislocation
Device occlusion
Freezing phenomenon
Gastric disorder (disease of stomach)
Hospitalisation
Joint dislocation (a joint position is changed from normal position)
Oropharyngeal pain

What are the common drug interactions of Sinemet and Aubagio, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Blood pressure increased
Cough
Deafness
Depressed mood
Dry throat
Dysstasia (difficulty in standing)
Gait disturbance
Nasopharyngitis (inflammation of the nasopharynx)
Nephrolithiasis (calculi in the kidneys)
Peroneal nerve palsy

60+:

Surgery
Alopecia (absence of hair from areas of the body)
Device dislocation
Device occlusion
Dyskinesia (abnormality or impairment of voluntary movement)
Fall
Freezing phenomenon
Headache (pain in head)
Hearing impaired
Memory impairment

What are the existing conditions these people have? *

Stress And Anxiety: 4 people, 22.22%
Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 22.22%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 16.67%
Muscle Spasms (muscle contraction): 3 people, 16.67%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 3 people, 16.67%
Urinary Tract Infection: 2 people, 11.11%
Oral Herpes (viral infection of mouth): 2 people, 11.11%
Constipation: 2 people, 11.11%
Dementia (madness): 2 people, 11.11%
Depression: 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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