Sinemet and Clexane drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Sinemet (carbidopa; levodopa) and Clexane (enoxaparin sodium). Common drug interactions include urinary tract infection among females and abdominal distension among males.
The phase IV clinical study analyzes what interactions people have when they take Sinemet and Clexane. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.
What is Sinemet?
Sinemet has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 29,601 Sinemet users. Check the latest studies of Sinemet.
What is Clexane?
Clexane has active ingredients of enoxaparin sodium. eHealthMe is studying from 14,679 Clexane users. Check the latest studies of Clexane.
26 people who take Sinemet and Clexane together, and have interactions are studied.

What are the common drug interactions of Sinemet and Clexane, by gender? *:
female:
- Urinary tract infection
- Vomiting
- Anal abscess
- Cerebral haemorrhage (bleeding within the brain)
- Dyskinesia (abnormality or impairment of voluntary movement)
- Keratoacanthoma (a common low-grade (unlikely to metastasize or invade) skin tumour that is believed to originate from the neck of the hair follicle)
- Pulmonary embolism (blockage of the main artery of the lung)
- Cardiac failure congestive
- Fatigue (feeling of tiredness)
- On and off phenomenon
male:
- Abdominal distension
- Abdominal pain
- Aphasia (damage to the parts of the brain that control language)
- Arthritis bacterial (form of joint disorder that involves inflammation of one or more joints due to bacterial infection)
- Asthenia (weakness)
- Blood pressure increased
- Cellulitis (infection under the skin)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Confusional state
- Death
What are the common drug interactions of Sinemet and Clexane, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Confusional state
- Hallucination, visual (seeing things that aren't there)
50-59:
n/a
60+:
- Urinary tract infection
- Vomiting
- Pathogen resistance
- Confusional state
- Delirium (wild excitement)
- Fall
- Foot fracture
- Hand fracture
- Joint injury
- Limb injury
What are the existing conditions these people have? *
- Dementia (madness): 4 people, 15.38%
- Pain: 3 people, 11.54%
- Depression: 3 people, 11.54%
- Vitamin D Decreased: 2 people, 7.69%
- Skin Exfoliation (removal of the oldest dead skin cells): 2 people, 7.69%
- Neuralgia (pain in one or more nerves): 2 people, 7.69%
- Insomnia (sleeplessness): 2 people, 7.69%
- Dry Skin: 2 people, 7.69%
- Constipation: 2 people, 7.69%
- Back Pain: 2 people, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Sinemet and Clexane?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Sinemet and Clexane:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Sinemet:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Clexane:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sinemet and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clexane and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on carbidopa; levodopa and enoxaparin sodium (the active ingredients of Sinemet and Clexane, respectively), and Sinemet and Clexane (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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