Sinemet and Daypro drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Sinemet (carbidopa; levodopa) and Daypro (oxaprozin). Common drug interactions include peripheral vascular disorder among females and anaemia among males.
The phase IV clinical study analyzes what interactions people have when they take Sinemet and Daypro. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.
What is Sinemet?
Sinemet has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 29,601 Sinemet users. Check the latest studies of Sinemet.
What is Daypro?
Daypro has active ingredients of oxaprozin. It is often used in osteoarthritis. eHealthMe is studying from 2,883 Daypro users. Check the latest studies of Daypro.
30 people who take Sinemet and Daypro together, and have interactions are studied.

What are the common drug interactions of Sinemet and Daypro, by gender? *:
female:
- Peripheral vascular disorder
- Platelet count decreased
- Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)
- Senile dementia (memory loss with ageing)
- Speech disorder
- Urinary tract infection
- Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
- Venous stasis (a condition of slow blood flow in the veins)
- Ventricular extrasystoles (premature cardiac contraction)
- Visual disturbance
male:
- Anaemia (lack of blood)
- Asthenia (weakness)
- Diabetes mellitus non-insulin-dependent
- Diarrhoea
- Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
- Dupuytren's contracture (thickening of the fibrous tissue layer underneath the skin of the palm and fingers)
- Ear infection
- Erectile dysfunction
- Fatigue (feeling of tiredness)
- Haematochezia (passage of stools containing blood)
What are the common drug interactions of Sinemet and Daypro, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Drug hypersensitivity
- Fall
- Confusion
- Contusion (a type of hematoma of tissue in which capillaries)
- Delusion (a false belief or opinion)
- Face injury
- Facial bones fracture (bone fracture of face)
- Loss of consciousness
- Peripheral swelling
- Anaemia (lack of blood)
* Approximation only. Some reports may have incomplete information.
Do you take Sinemet and Daypro?
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- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Sinemet and Daypro:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Sinemet:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Daypro:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sinemet and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Daypro and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on carbidopa; levodopa and oxaprozin (the active ingredients of Sinemet and Daypro, respectively), and Sinemet and Daypro (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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