Sinemet and Gaviscon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sinemet (carbidopa; levodopa) and Gaviscon (aluminum hydroxide; magnesium trisilicate). Common drug interactions include affective disorder among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Sinemet and Gaviscon. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Sinemet?

Sinemet has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 29,601 Sinemet users. Check the latest studies of Sinemet.

What is Gaviscon?

Gaviscon has active ingredients of aluminum hydroxide; magnesium trisilicate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 12,355 Gaviscon users. Check the latest studies of Gaviscon.

On Jul, 25, 2026

36 people who take Sinemet and Gaviscon together, and have interactions are studied.

What are the common drug interactions of Sinemet and Gaviscon, by gender? *:

female:

Affective disorder (mental disorder)
Agitation (state of anxiety or nervous excitement)
Antiphospholipid syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss)
Arteriospasm coronary (spasm of the large- or medium-sized coronary arteries)
Arthralgia (joint pain)
Asthma
Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Back disorder
Balance disorder

male:

Dyspnoea (difficult or laboured respiration)
Arthralgia (joint pain)
Dysphagia (a condition in which swallowing is difficult or painful)
Gastric ulcer perforation (stomach hole due to ulcer)
Haemoglobin decreased
Heart rate irregular
Hyperhidrosis (abnormally increased sweating)
Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Lung consolidation (a condition whereby the lung tissues solidify because of the accumulation of solid and liquid material in the air spaces)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

What are the common drug interactions of Sinemet and Gaviscon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Antiphospholipid syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss)
Anxiety
Arteriospasm coronary (spasm of the large- or medium-sized coronary arteries)
Arthralgia (joint pain)
Asthma
Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Back pain
Blood glucose decreased
Breath odour

50-59:

Agitation (state of anxiety or nervous excitement)
Bradycardia (abnormally slow heart action)
Chronic kidney disease
Constipation
Dehydration (dryness resulting from the removal of water)
Fall
Muscle spasms (muscle contraction)
Pain

60+:

Bone pain
Dizziness
Abdominal pain
Abdominal tenderness
Arthralgia (joint pain)
Dyspnoea (difficult or laboured respiration)
Eye infection toxoplasmal (a germ called toxoplasma can cause infection within the eye)
Miosis (constriction of the pupil of the eye, resulting from a normal response to an increase in light)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pneumoperitoneum (air or gas in the abdominal (peritoneal) cavity)

What are the existing conditions these people have? *

Stress And Anxiety: 4 people, 11.11%
Pain: 3 people, 8.33%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 5.56%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 5.56%
Panic Disorder: 2 people, 5.56%
Hypersensitivity: 2 people, 5.56%
Fever: 2 people, 5.56%
Faeces Hard: 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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