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Sinemet and Hizentra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sinemet (carbidopa; levodopa) and Hizentra (human immunoglobulin g). Common drug interactions include pruritus among females and secretion discharge among males.

The phase IV clinical study analyzes what interactions people have when they take Sinemet and Hizentra. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Sinemet?

Sinemet has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 29,601 Sinemet users. Check the latest studies of Sinemet.

What is Hizentra?

Hizentra has active ingredients of human immunoglobulin g. eHealthMe is studying from 23,666 Hizentra users. Check the latest studies of Hizentra.

On Jul, 07, 2026

20 people who take Sinemet and Hizentra together, and have interactions are studied.

Sinemet and Hizentra drug interactions.

What are the common drug interactions of Sinemet and Hizentra, by gender? *:

female:

  1. Pruritus (severe itching of the skin)
  2. Rash
  3. Swelling
  4. Urticaria (rash of round, red welts on the skin that itch intensely)
  5. Death
  6. Intestinal obstruction
  7. Stent placement
  8. Contusion (a type of hematoma of tissue in which capillaries)
  9. Ear infection
  10. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

male:

  1. Secretion discharge
  2. Sinusitis (inflammation of sinus)
  3. Somnolence (a state of near-sleep, a strong desire for sleep)
  4. Cardiac disorder
  5. Dyspnoea (difficult or laboured respiration)

What are the common drug interactions of Sinemet and Hizentra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

60+:

  1. Hordeolum (small collection of pus (abscess) on the eyelid)
  2. Rash
  3. Urticaria (rash of round, red welts on the skin that itch intensely)
  4. Death
  5. Contusion (a type of hematoma of tissue in which capillaries)
  6. Ear infection

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 13 people, 65.00%
  2. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 2 people, 10.00%
  3. Multiple Myeloma (cancer of the plasma cells): 1 person, 5.00%
  4. Movement - Uncontrolled Or Slow: 1 person, 5.00%
  5. Immune System Disorder: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Sinemet and Hizentra?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Sinemet and Hizentra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sinemet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hizentra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sinemet and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hizentra and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on carbidopa; levodopa and human immunoglobulin g (the active ingredients of Sinemet and Hizentra, respectively), and Sinemet and Hizentra (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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