Sinemet and Ms contin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sinemet (carbidopa; levodopa) and Ms contin (morphine sulfate). Common drug interactions include swelling among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Sinemet and Ms contin. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Sinemet?

Sinemet has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 29,601 Sinemet users. Check the latest studies of Sinemet.

What is Ms contin?

Ms contin has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 69,289 Ms contin users. Check the latest studies of Ms contin.

On Jul, 09, 2026

45 people who take Sinemet and Ms contin together, and have interactions are studied.

Sinemet and Ms contin drug interactions.

What are the common drug interactions of Sinemet and Ms Contin, by gender? *:

female:

Swelling
Syncope (loss of consciousness with an inability to maintain postural tone)
Tenderness (pain or discomfort when an affected area is touched)
Thyroid cancer
Thyroid neoplasm (tumour of thyroid)
Tooth extraction
Tooth infection
Unresponsive to stimuli
Vaginal infection
Vertigo

male:

Pneumonia
Death
Abnormal dreams
Abscess (pus)
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Anaemia (lack of blood)
Bladder spasm
Blood alkaline phosphatase increased
Blood creatinine increased
Blood sodium decreased

What are the common drug interactions of Sinemet and Ms Contin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Oedema (fluid collection in tissue)
Oedema peripheral (superficial swelling)
Oral infection
Oral pain
Osteomyelitis (infection of bone)
Pain in jaw
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Postmenopausal haemorrhage (post-menopausal bleeding)
Primary sequestrum (piece of dead bone that has become separated during the process of necrosis from normal/sound bone)

60+:

Pneumonia
Confusional state
Coronary artery bypass
Dysphagia (a condition in which swallowing is difficult or painful)
Heart valve replacement
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Urinary tract infection
Abnormal behaviour
Gait disturbance
Memory impairment

What are the existing conditions these people have? *

High Blood Pressure: 14 people, 31.11%
Metastases To Bone (cancer spreads to bone): 11 people, 24.44%
Breast Cancer: 11 people, 24.44%
Bone Pain: 11 people, 24.44%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 11 people, 24.44%
Constipation: 10 people, 22.22%
Lung Cancer - Non-Small Cell (lung cancer): 8 people, 17.78%
Hallucinations (sensations that appear real but are created by your mind): 4 people, 8.89%
Delusion (a false belief or opinion): 4 people, 8.89%
Urination - Painful: 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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