Sinemet and Paracetamol drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Sinemet (carbidopa; levodopa) and Paracetamol (acetaminophen). Common drug interactions include fatigue among females and fall among males.
The phase IV clinical study analyzes what interactions people have when they take Sinemet and Paracetamol. It is created by eHealthMe based on reports of 273 people who take the same drugs from the FDA, and is updated regularly.
What is Sinemet?
Sinemet has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 29,601 Sinemet users. Check the latest studies of Sinemet.
What is Paracetamol?
Paracetamol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 115,650 Paracetamol users. Check the latest studies of Paracetamol.
273 people who take Sinemet and Paracetamol together, and have interactions are studied.

What are the common drug interactions of Sinemet and Paracetamol, by gender? *
What are the common drug interactions of Sinemet and Paracetamol, by age (0-1 to 60+)? *
What are the existing conditions these people have? *
* Approximation only. Some reports may have incomplete information.
Do you take Sinemet and Paracetamol?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Sinemet (29,601 reports)
- Paracetamol (115,650 reports)
Browse all drug interactions of Sinemet and Paracetamol:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Sinemet:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Paracetamol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sinemet and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Paracetamol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on carbidopa; levodopa and acetaminophen (the active ingredients of Sinemet and Paracetamol, respectively), and Sinemet and Paracetamol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Could Xifaxan cause Immunosuppressant Drug Level Decreased? - 18 seconds ago
- Could Aredia cause Colitis Ulcerative Aggravated? - 24 seconds ago
- Could Prochlorperazine cause Leukopenia? - 28 seconds ago
- Drug interactions of Vasopressin and Asa - 43 seconds ago
- Could Prednisone cause Heart Rate Increased? - 44 seconds ago
- Could Ibu cause Immune Reconstitution Syndrome? - 48 seconds ago
- Could Tadalafil cause Acne? - 58 seconds ago
- Could Menest cause Insomnia? - 59 seconds ago
- Dhc Plus vs. Fentanyl, side effect and effectiveness comparison - a minute ago
- Could Tazidime cause Gallstones? - a minute ago