Sinemet and Phenazopyridine hcl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sinemet (carbidopa; levodopa) and Phenazopyridine hcl (phenazopyridine hydrochloride). Common drug interactions include nausea among females.

The phase IV clinical study analyzes what interactions people have when they take Sinemet and Phenazopyridine hcl. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Sinemet?

Sinemet has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 29,601 Sinemet users. Check the latest studies of Sinemet.

What is Phenazopyridine hcl?

Phenazopyridine hcl has active ingredients of phenazopyridine hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 1,588 Phenazopyridine hcl users. Check the latest studies of Phenazopyridine hcl.

On Jul, 17, 2026

14 people who take Sinemet and Phenazopyridine hcl together, and have interactions are studied.

Sinemet and Phenazopyridine hcl drug interactions.

What are the common drug interactions of Sinemet and Phenazopyridine Hcl, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Back pain
Decreased appetite
Depression
Dysphagia (a condition in which swallowing is difficult or painful)
Fatigue (feeling of tiredness)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Myalgia (muscle pain)
Oedema peripheral (superficial swelling)
Swelling

male:

n/a

What are the common drug interactions of Sinemet and Phenazopyridine Hcl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Depression
Dyspepsia (indigestion)
Emotional disorder
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Gastritis erosive (a break in the surface layer of the membrane lining the stomach with infection)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Headache (pain in head)
Hypertension (high blood pressure)
Hypoaesthesia (reduced sense of touch or sensation)
Myalgia (muscle pain)

50-59:

Alopecia (absence of hair from areas of the body)
Anaemia (lack of blood)
Constipation
Decreased appetite
Diarrhoea
Diplopia (double vision)
Dizziness
Dysphagia (a condition in which swallowing is difficult or painful)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Fall

60+:

n/a

What are the existing conditions these people have? *

High Blood Pressure: 10 people, 71.43%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 9 people, 64.29%
Bone Pain: 9 people, 64.29%
Pain: 9 people, 64.29%
Metastases To Bone (cancer spreads to bone): 9 people, 64.29%
Breast Cancer: 9 people, 64.29%
Constipation: 9 people, 64.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 14.29%
Bladder Pain: 1 person, 7.14%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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