Sinemet and Proventil drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Sinemet (carbidopa; levodopa) and Proventil (albuterol). Common drug interactions include urinary tract infection among females and hallucination among males.
The phase IV clinical study analyzes what interactions people have when they take Sinemet and Proventil. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.
What is Sinemet?
Sinemet has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 29,601 Sinemet users. Check the latest studies of Sinemet.
What is Proventil?
Proventil has active ingredients of albuterol. It is often used in asthma. eHealthMe is studying from 16,110 Proventil users. Check the latest studies of Proventil.
52 people who take Sinemet and Proventil together, and have interactions are studied.

What are the common drug interactions of Sinemet and Proventil, by gender? *:
female:
- Urinary tract infection
- Headache (pain in head)
- Blood creatinine increased
- Blood lactic acid increased
- Cardiac failure congestive
- Cellulitis (infection under the skin)
- Chronic kidney disease
- Coagulopathy (blood's ability to clot is impaired)
- Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
- Constipation
male:
- Hallucination (an experience involving the perception of something not present)
- Fall
- Pyrexia (fever)
- Urinary tract infection
- Anaemia (lack of blood)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Cardiac failure congestive
- Cellulitis (infection under the skin)
- Cerebrospinal fluid leakage
What are the common drug interactions of Sinemet and Proventil, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Pyrexia (fever)
- Cerebrospinal fluid leakage
- Implant site infection
- Implant site swelling
- Staphylococcal infection (an infection with staphylococcus bacteria)
- Vomiting
- Abdominal pain
- Cellulitis (infection under the skin)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Diarrhoea
20-29:
n/a
30-39:
n/a
40-49:
- Cellulitis (infection under the skin)
- Cellulitis gangrenous (localized inflammation of the soft or connective tissue with considerable mass of body tissue dies (necrosis))
- Gangrene (body tissue dies)
- Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
- Perineal abscess
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Urinary tract infection
- Vulval abscess
- Vulval cellulitis (inflammation of skin around vagina)
- Vulvitis (inflammation of the vulva)
50-59:
- Hip arthroplasty
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Bone density decreased
- Cerebral haemorrhage (bleeding within the brain)
- Chronic kidney disease
- Dyspepsia (indigestion)
- Emotional distress
- Fear of falling
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
60+:
- Hallucination (an experience involving the perception of something not present)
- Vomiting
- Confusional state
- Constipation
- Dehydration (dryness resulting from the removal of water)
- Hip fracture
- Muscle spasms (muscle contraction)
- Headache (pain in head)
- Anxiety
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
What are the existing conditions these people have? *
- Wheezing (a high-pitched whistling sound made while you breath): 11 people, 21.15%
- Pain: 10 people, 19.23%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 15.38%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 15.38%
- Nausea (feeling of having an urge to vomit): 5 people, 9.62%
- Dyspnea (difficult or laboured breathing): 5 people, 9.62%
- Osteoporosis (bones weak and more likely to break): 4 people, 7.69%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 5.77%
- Hypersensitivity: 3 people, 5.77%
- Hallucinations (sensations that appear real but are created by your mind): 3 people, 5.77%
* Approximation only. Some reports may have incomplete information.
Do you take Sinemet and Proventil?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Sinemet and Proventil:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Sinemet:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Proventil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sinemet and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Proventil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on carbidopa; levodopa and albuterol (the active ingredients of Sinemet and Proventil, respectively), and Sinemet and Proventil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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