Sinemet and Zoledronic drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sinemet (carbidopa; levodopa) and Zoledronic (zoledronic acid). Common drug interactions include pyrexia among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Sinemet and Zoledronic. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Sinemet?

Sinemet has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 29,601 Sinemet users. Check the latest studies of Sinemet.

What is Zoledronic?

Zoledronic has active ingredients of zoledronic acid. eHealthMe is studying from 29,812 Zoledronic users. Check the latest studies of Zoledronic.

On Aug, 11, 2026

12 people who take Sinemet and Zoledronic together, and have interactions are studied.

Sinemet and Zoledronic drug interactions.

What are the common drug interactions of Sinemet and Zoledronic, by gender? *:

female:

Pyrexia (fever)
Delusion (a false belief or opinion)
Dyskinesia (abnormality or impairment of voluntary movement)
Hallucination, visual (seeing things that aren't there)
Hyperhidrosis (abnormally increased sweating)
Hyperkalaemia (damage to or disease of the kidney)
Hypertension (high blood pressure)
Psychotic disorder
Renal failure (kidney dysfunction)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)

male:

Anaemia (lack of blood)
Decreased appetite
Rib fracture
Thrombocytopenia (decrease of platelets in blood)
Vision blurred
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Hallucination (an experience involving the perception of something not present)
Neuropathy peripheral (surface nerve damage)

What are the common drug interactions of Sinemet and Zoledronic, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Cellulitis (infection under the skin)

50-59:

Decreased appetite
Hallucination (an experience involving the perception of something not present)

60+:

Disease progression
Dyspnoea (difficult or laboured respiration)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Confusional state
Contusion (a type of hematoma of tissue in which capillaries)
Drug ineffective
Fall
Haematoma (collection of blood outside the blood vessels)
Hip arthroplasty
Hip fracture

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 4 people, 33.33%
Osteoporosis (bones weak and more likely to break): 3 people, 25.00%
Self Injurious Behavior: 2 people, 16.67%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 16.67%
Macular Degeneration (painless eye condition that leads to the gradual loss of central vision): 2 people, 16.67%
Depression: 2 people, 16.67%
High Blood Pressure: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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