Singulair and Arg drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Singulair (montelukast sodium) and Arg (l - arginine). Common drug interactions include pain in extremity among females and diarrhoea among males.
The phase IV clinical study analyzes what interactions people have when they take Singulair and Arg. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.
What is Singulair?
Singulair has active ingredients of montelukast sodium. It is often used in asthma. eHealthMe is studying from 129,752 Singulair users. Check the latest studies of Singulair.
What is Arg?
Arg has active ingredients of l - arginine. eHealthMe is studying from 2,664 Arg users. Check the latest studies of Arg.
57 people who take Singulair and Arg together, and have interactions are studied.

What are the common drug interactions of Singulair and Arg, by gender? *:
female:
- Pain in extremity
- Pelvic adhesions
- Pneumonia
- Skin exfoliation (removal of the oldest dead skin cells)
- Adenomyosis (presence of ectopic glandular tissue found in muscle)
- Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)
- Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Bone density decreased
- Cardiac failure
male:
- Diarrhoea
- Nausea (feeling of having an urge to vomit)
- Blood glucose increased
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Dizziness
- Feeling jittery
- Flushing (the warm, red condition of human skin)
- Hypersensitivity
- Influenza
- Injection site haemorrhage (bleeding from injection site)
What are the common drug interactions of Singulair and Arg, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Abnormal behaviour
- Blood glucose decreased
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Irritability
- Mood swings (an extreme or rapid change in mood)
- Nightmare (unpleasant dream)
10-19:
- Abnormal faeces (abnormal stool)
- Drug ineffective
- Hyperammonaemia
- Menstruation irregular
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Urine abnormality
20-29:
- Abdominal discomfort
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Multiple allergies (allergy to multiple agents)
- Nasal septum deviation (deviated nasal septum)
30-39:
- Cardiac infection (an infection of the heart)
- Cerebral disorder (brain disease)
- Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)
- Headache (pain in head)
- Malaise (a feeling of general discomfort or uneasiness)
- Nasal septum deviation (deviated nasal septum)
- Pelvic adhesions
- Surgery
- Adenomyosis (presence of ectopic glandular tissue found in muscle)
- Cardiac failure
40-49:
- Blindness
- Choking (mechanical obstruction of the flow of air from the environment into the lungs)
- Dizziness
- Eye pain
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Hypoaesthesia (reduced sense of touch or sensation)
- Hypotension (abnormally low blood pressure)
- Oropharyngeal spasm (contraction of oropharynx)
- Pneumonia
50-59:
- Joint swelling
- Arthralgia (joint pain)
- Back pain
- Diarrhoea
- Eye pruritus (eye itching)
- Food allergy
- Frequent bowel movements
- Headache (pain in head)
- Joint stiffness
- Lip disorder (disease of lip)
60+:
- Abdominal pain upper
- Pain in extremity
- Injection site haemorrhage (bleeding from injection site)
- Myalgia (muscle pain)
- Nausea (feeling of having an urge to vomit)
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Weight fluctuation
- Weight increased
- Malaise (a feeling of general discomfort or uneasiness)
- Arthralgia (joint pain)
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 18 people, 31.58%
- Immunodeficiency Common Variable: 10 people, 17.54%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 17.54%
- Hypersensitivity: 9 people, 15.79%
- Itching: 7 people, 12.28%
- Breast Cancer Female: 6 people, 10.53%
- Immunodeficiency: 4 people, 7.02%
- Pain: 3 people, 5.26%
- Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 5.26%
- Depression: 3 people, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Singulair and Arg?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Singulair and Arg:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Singulair:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Arg:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Singulair and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Arg and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Das S, Mondal S, Dey JK, Bandyopadhyay S, Saha I, Tripathi SK, "A case of montelukast induced hypercholesterolemia, severe hypertriglyceridemia and pancreatitis", Journal of Young Pharmacists, 2013 Jun .
- Das S, Mondal S, Dey JK, Bandyopadhyay S, Saha I, Tripathi SK, "A case of montelukast induced hypercholesterolemia, severe hypertriglyceridemia and pancreatitis", Journal of Young Pharmacists, 2013 Jun .
How the study uses the data?
The study uses data from the FDA. It is based on montelukast sodium and l - arginine (the active ingredients of Singulair and Arg, respectively), and Singulair and Arg (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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